{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:54:01Z","timestamp":1790276041986,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":232,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100022965","name":"Ministerio de Ciencia, Tecnolog\u00eda e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["891"],"award-info":[{"award-number":["891"]}],"id":[{"id":"10.13039\/100022965","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Microbiology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    complex species are the main cause of candidiasis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    The purpose of this study was to report the prevalence and genetic diversity of\n                    <jats:italic>C. albicans<\/jats:italic>\n                    complex using hyphal wall protein 1 (HWP1) gene size polymorphism, as well as the susceptibility patterns to fluconazole and voriconazole.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    A total of 170 yeast isolates were obtained from vulvovaginal samples, and phenotypic and proteomic identification was performed.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Most clinical isolates were\n                    <jats:italic>C. albicans<\/jats:italic>\n                    complex (\n                    <jats:italic>n<\/jats:italic>\n                    = 153) followed by\n                    <jats:italic>C. glabrata<\/jats:italic>\n                    (\n                    <jats:italic>n<\/jats:italic>\n                    = 13),\n                    <jats:italic>C. parapsilosis<\/jats:italic>\n                    complex (\n                    <jats:italic>n<\/jats:italic>\n                    = 2), and\n                    <jats:italic>Pichia kudriavzevii<\/jats:italic>\n                    (\n                    <jats:italic>n<\/jats:italic>\n                    = 2). Among\n                    <jats:italic>C. albicans<\/jats:italic>\n                    complexes, all isolates were\n                    <jats:italic>C. albicans sensu stricto<\/jats:italic>\n                    and 2.61% and 4.58% were resistant to fluconazole and voriconazole, respectively.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    The presence of different alleles was confirmed, heterozygosity was more common than homozygosity (71.03% vs. 28.97%), and some isolates showed a homozygosis pattern not previously described. Despite these genetic diversities, no specific genotype was linked to azole resistance.\n                  <\/jats:p>","DOI":"10.1155\/ijm\/8507361","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T09:38:32Z","timestamp":1755769112000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["HWP1 Gene Sequence Diversity and Antifungal Susceptibility Patterns in Colombian Vulvovaginal Isolates of the\n                    <i>Candida albicans<\/i>\n                    Species Complex"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4402-041X","authenticated-orcid":false,"given":"Soraya","family":"Morales-L\u00f3pez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeneiris","family":"Villero Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulibeth","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyner","family":"Lechuga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Caicedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Garc\u00eda-Effron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,21]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12281-021-00415-9"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/1040841X.2015.1091805"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.18359\/rmed.6314"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ram.2022.08.003"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12281-018-0329-6"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.5935\/1676-2444.20160039"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-024-03217-6"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000834"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof4040138"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e03619"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13280"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.674765"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/iyaa004"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2008.05.014"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01540-08"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2008.01630.x"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.5812\/jjm.66240"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ram.2015.10.003"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.18869\/acadpub.cmm.2.4.1"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12266"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myw108"},{"key":"e_1_2_9_22_2","volume-title":"The Yeasts: A Taxonomic Study","author":"Kurtzman C. 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