{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:38:51Z","timestamp":1773005931446,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"vor","delay-in-days":99,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["206\/2018"],"award-info":[{"award-number":["206\/2018"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Purpose:<\/jats:bold>\n                    This study aims to verify the stability of different types of fluoride in a dentifrice containing Brazilian red propolis (BRP).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    The dentifrice formulation was developed with calcium carbonate (CaCO\n                    <jats:sub>3<\/jats:sub>\n                    ) and sodium monofluorophosphate (MFP) (patent INPI BR1020170110974). Nominal fluoride content was 1500 \u03bcg\/g. Batches of five lots were selected and analyzed for 2 consecutive years (fresh, with 12 and 24 months). Dentifrices from each tube were analyzed in duplicate using an ion\u2010specific electrode (ISE). The concentrations of fluoride (total fluoride [TF], total soluble fluoride [TSF], and ionizable fluoride [IF]) were determined, and the results were expressed in ppm\u2009F (\u03bcgF\/g).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    After 12 months of aging, the samples showed TF concentration ranging from 1198.9\u2009\u00b1\u200926.9 to 1443.6\u2009\u00b1\u200933.4\u2009ppm F, TSF ranging from 869.6\u2009\u00b1\u2009105.5 to 965.8\u2009\u00b1\u2009149.8\u2009ppm F, and IF ranging from 223.5\u2009\u00b1\u200914.8 to 269.7\u2009\u00b1\u200910.1\u2009ppm F. After 24 months of aging, the samples showed TF concentration ranging from 763.5\u2009\u00b1\u200973.2 to 1083.1\u2009\u00b1\u200932.4\u2009ppm F, TSF ranging from 552.3\u2009\u00b1\u200939.9 to 758.4\u2009\u00b1\u2009141.1\u2009ppm F, and IF ranging from 102.2\u2009\u00b1\u20094.0 to 174.7\u2009\u00b1\u20094.9\u2009ppm F.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Soluble fluoride remained relatively stable until 12 months of aging; however, at 24 months of aging, the concentration reduced.\n                  <\/jats:p>","DOI":"10.1155\/ijod\/3414733","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:35:26Z","timestamp":1744259726000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fluoride Content, Availability, and Stability in a Propolis\u2010Based Dentifrice"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9681-1761","authenticated-orcid":false,"given":"Mara Assef Leit\u00e3o","family":"Lotif","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3568-3089","authenticated-orcid":false,"given":"Lidia Audrey Rocha","family":"Valadas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8538-9868","authenticated-orcid":false,"given":"Peter","family":"Bottenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-5805","authenticated-orcid":false,"given":"Aldo","family":"Squassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-2484","authenticated-orcid":false,"given":"Thereza Cristina Farias Botelho","family":"Dantas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5121-0436","authenticated-orcid":false,"given":"Vanara Flor\u00eancio","family":"Passos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1228-2669","authenticated-orcid":false,"given":"Edilson Martins","family":"Rodrigues Neto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4301-4739","authenticated-orcid":false,"given":"Mary Anne Medeiros","family":"Bandeira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2570-9265","authenticated-orcid":false,"given":"Marta Maria de Fran\u00e7a","family":"Fonteles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.9790\/0853-1603071518"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2018.12.004"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2015.10.019"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-016-1905-5"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.2174\/1872208313666190826145453"},{"key":"e_1_2_11_6_2","first-page":"1329","article-title":"Caseinates Loaded with Brazilian Red Propolis Extract: Preparation, Protein-Flavonoids Interaction","volume":"147","author":"Nascimento T. 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