{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:38:14Z","timestamp":1773005894585,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":330,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This pilot study investigated the effects of\u2009\u22656 weeks after nonsurgical treatment of the tissues surrounding dental implants, using clinical traditional methods and the aMMP\u20108 test technology in 39 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Materials<\/jats:title>\n                    <jats:p>In the peri\u2010implant pocket of 39 dental implants, an aMMP\u20108 concentration, gingival bleeding (BOP), and implant pocket depth (PPD), and an x\u2010ray for radiologic bone level (RBL) were taken. The \u22656 weeks after nonsurgical treatment of the implants was carried out, and the treatment response was evaluated again after 30 days using the same methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The \u22656 weeks after nonsurgical treatment achieved a decrease in the aMMP\u20108 enzyme level, BOP, and the implant pockets. After 1 month, no statistically significant positive changes were observed in the result of the BOP (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.02) or the depth of deepened implant pockets (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.02) without the effect of surgical treatment, but there was a statistically significant reduction in the levels of the aMMP\u20108 chair\u2010side test (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Signs of inflammation were found to be very common in the tissues surrounding the implant. Getting the peri\u2010implant tissue healthy in \u22656 weeks after nonsurgical treatment with traditional nonsurgical treatment would seem to be surprisingly challenging. The applicability of the aMMP\u20108 enzyme test in diagnosing and reading the real\u2010time health status of the surrounding tissues in monitoring \u22656 weeks after nonsurgical treatments provides a useful and accurate method to control the health and disease.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      ClinicalTrials.gov Identifier: NCT06408467\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/ijod\/6681032","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T10:37:31Z","timestamp":1764239851000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Monitoring of Nonsurgical Treatment of Peri\u2010Implantitis Traditional Measurement Methods and aMMP\u20108 Test Technology: A Pilot Study"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7914-9726","authenticated-orcid":false,"given":"Hanna","family":"L\u00e4hteenm\u00e4ki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5821-5299","authenticated-orcid":false,"given":"Ismo T.","family":"R\u00e4is\u00e4nen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taina","family":"Tervahartiala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2994-8690","authenticated-orcid":false,"given":"Pirjo","family":"P\u00e4rn\u00e4nen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2219-4689","authenticated-orcid":false,"given":"Tommi","family":"P\u00e4til\u00e4","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7914-3052","authenticated-orcid":false,"given":"Timo","family":"Sorsa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01283.x"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12334"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12369"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12049"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.150071"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/bios10050044"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008676.pub2"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/idh.12432"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ebd.6401216"},{"key":"e_1_2_12_10_2","unstructured":"AlassiriS. 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