{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:45:48Z","timestamp":1793814348783,"version":"4.6.1"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":221,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100023915","name":"Faculty of Dentistry, Chulalongkorn University","doi-asserted-by":"publisher","award":["DRF 68_039"],"award-info":[{"award-number":["DRF 68_039"]}],"id":[{"id":"10.13039\/501100023915","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare microtensile bond strength at different time points relative to fractional irradiation using both etch\u2010and\u2010rinse (ER) and self\u2010etch (SE) adhesive systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Ninety\u2010six sound extracted human molars were divided into two control groups (control\u2010ER and control\u2010SE) and six irradiated groups. The irradiated groups were subdivided based on the timing of restoration: those restored before irradiation (restoration before irradiation [RBI]\u2010ER and RBI\u2010SE) and those restored after irradiation (irradiation before restoration [IBR]\u2010ER, IBR\u2010ER delayed, IBR\u2010SE, and IBR\u2010SE delayed). The irradiated specimens underwent fractional radiotherapy at 2\u2009Gy per day, reaching a total dose of 70\u2009Gy. All specimens were restored with resin composite at the designated time points relative to irradiation. Microtensile bond strength was measured, fracture patterns were analyzed, and surface morphology was examined using scanning electron microscopy (SEM). Data were analyzed using two\u2010way ANOVA followed by Bonferroni post hoc tests (\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u2009=\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      ANOVA revealed significant restoration timing and adhesive\u2010type effects on microtensile bond strength (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.01). Post hoc analysis showed that irradiation reduced bond strength (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.01). In irradiated ER groups, the RBI group had lower bond strength than post\u2010irradiation restorations (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.01), while in SE groups, bond strength did not vary across time points (\n                      <jats:italic>p<\/jats:italic>\n                      &gt; 0.05). Additionally, significant differences were found in the IBR and IBR delayed groups, with the ER adhesive outperforming the SE adhesive with a (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Irradiation compromised dentin bond strength, resin tag formation and hybrid layer integrity in a manner dependent on the adhesive system used. In the ER adhesive groups, bond strength was significantly higher when restorations were performed post\u2010irradiation. Conversely, for the SE adhesive groups, the time points of the restoration had no significant effect on bond strength.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/ijod\/6925650","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T09:02:33Z","timestamp":1786352553000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Effect of Radiotherapy on the Microtensile Bond Strength of Dentin in Relation to the Timing of Restoration Procedure"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3535-5624","authenticated-orcid":false,"given":"Phatchara","family":"Tangviroon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6764-1036","authenticated-orcid":false,"given":"Chawalid","family":"Pianmee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1649-6357","authenticated-orcid":false,"given":"Thanaphum","family":"Osathanon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supapan","family":"Wittayanuwat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0709-875X","authenticated-orcid":false,"given":"Wisarut","family":"Prawatvatchara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6170-5053","authenticated-orcid":false,"given":"Dusit","family":"Nantanapiboon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.4103\/0975-5950.183870"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2018.08.018"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-019-5614-4"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1221"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2011.03.003"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2022.04.014"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-024-05404-1"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1746414"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/798972"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.3290\/j.jad.a11372"},{"key":"e_1_2_13_11_2","first-page":"69","article-title":"Radiotherapy Impairs Adhesive Bonding in Primary Teeth: An In Vitro Study","volume":"87","author":"Mellara T. 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