{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:37:29Z","timestamp":1773005849308,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100015034","name":"Shahid Sadoughi University of Medical Sciences","doi-asserted-by":"publisher","award":["IR.SSU.REC.1400.004"],"award-info":[{"award-number":["IR.SSU.REC.1400.004"]}],"id":[{"id":"10.13039\/501100015034","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Investigating the pattern of extension in the periapical (PA) inflammatory lesions is important in the treatment plan and prognosis of treatment.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Introduction:<\/jats:bold>\n                    This study evaluated the topography of PA inflammatory lesions in the first molars using cone\u2010beam computed tomography (CBCT).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    In this descriptive study, 197 CBCT images about patients in the age group of 14\u201377 years were analyzed. The maximum extension of the PA lesion in the three orthogonal planes related to the regions of maxillary and mandibular first molars was measured and reported in millimeters. Measurements were compared based on age, gender, dental arch, and root type. Statistical analysis was performed using percentages, repeated measure ANOVA, paired\n                    <jats:italic>t<\/jats:italic>\n                    \u2010tests, and Pearson correlation coefficient. The significant level was set at 0.05.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    The highest total mean lesion extensions were in the vertical plane followed by the buccolingual and mesiodistal plane. There was a statistically significant difference between the extension of the PA lesion in the vertical and mesiodistal (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001), vertical and buccolingual (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 = 0.001), as well as the mesiodistal and buccolingual planes (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 = 0.027). In the maxilla and mandible, the highest mean lesion extension was in the vertical, buccolingual, and mesiodistal plane, respectively. According to the root type, there was only a statistically significant difference in lesion extension in the buccolingual plane and between the mesial and distobuccal roots (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 = 0.030).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Given the limitations of the present study, regarding the extension of the PA lesion in the first molar region, the bone structure of the maxilla and mandible follows a precise and delicate pattern. In this regard, future studies in different communities and races should be designed to address this issue in different communities. In addition, CBCT is a reliable imaging method to evaluate the extension of the PA lesion both morphologically and morphometrically.\n                  <\/jats:p>","DOI":"10.1155\/ijod\/8992304","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T02:22:21Z","timestamp":1737426141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Topographic Evaluation of Inflammatory Periapical Lesions in the First Molar\u2019s Region Using CBCT"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3543-9537","authenticated-orcid":false,"given":"Maryam","family":"Kazemipoor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7953-4192","authenticated-orcid":false,"given":"Fatemeh","family":"Foroughipour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3200-0905","authenticated-orcid":false,"given":"Yaser","family":"Safi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"key":"e_1_2_14_1_2","doi-asserted-by":"publisher","DOI":"10.14744\/eej.2020.42714"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/jimaging8100290"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12388"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2020.03.025"},{"key":"e_1_2_14_5_2","first-page":"e773","article-title":"Two-Dimensional Periapical, Panoramic Radiography Versus Three-Dimensional Cone-Beam Computed Tomography in the Detection of Periapical Lesion After Endodontic Treatment: A Systematic Review","volume":"12","author":"Antony D. P.","year":"2020","journal-title":"Cureus"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.17219\/dmp\/143546"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2006.01157.x"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.908970"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2019.2.23602"},{"key":"e_1_2_14_10_2","doi-asserted-by":"crossref","unstructured":"OzkanB. T. CelikS. andDurmusE. Paresthesia of the Mental Nerve Stems from Periapical Infection of Mandibular Canine Tooth: A Case Report Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology 2008 105 no. 5 e28\u2013e31.","DOI":"10.1016\/j.tripleo.2008.01.023"},{"key":"e_1_2_14_11_2","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20587"},{"key":"e_1_2_14_12_2","doi-asserted-by":"crossref","unstructured":"BordeaI. R. HannaR. andChiniforushN. et al.Evaluation of the Outcome of Various Laser Therapy Applications in Root Canal Disinfection: A Systematic Review Photo Diagnosis and Photodynamic Therapy 2020 29 no. 10 11\u201319.","DOI":"10.1016\/j.pdpdt.2019.101611"},{"key":"e_1_2_14_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-011-0671-3"},{"key":"e_1_2_14_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13216"},{"key":"e_1_2_14_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-012-0393-3"},{"key":"e_1_2_14_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/0300060519860960"},{"key":"e_1_2_14_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2019.12.004"},{"key":"e_1_2_14_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2007.01299.x"},{"key":"e_1_2_14_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13256"},{"key":"e_1_2_14_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2344-y"},{"key":"e_1_2_14_21_2","first-page":"259","article-title":"Pattern of Endodontic Periapical Lesion Extension in Anterior Teeth: A CBCT Study in an Iranian Population","volume":"14","author":"Kazemipoor M.","year":"2019","journal-title":"Iranian Endodontic Journal"},{"key":"e_1_2_14_22_2","doi-asserted-by":"publisher","DOI":"10.2174\/1573405617666210225090213"},{"key":"e_1_2_14_23_2","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51228"},{"key":"e_1_2_14_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/adj.12018"},{"key":"e_1_2_14_25_2","doi-asserted-by":"publisher","DOI":"10.4103\/2231-0762.161753"},{"key":"e_1_2_14_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3649"},{"key":"e_1_2_14_27_2","doi-asserted-by":"crossref","unstructured":"KazemipoorM. ForoughipourF. andSafiY. Topographic Evaluation of Periapical Inflammatory Lesions in the First Molar\u2019s Region Using Cbct 2024 https:\/\/doi.org\/10.2139\/ssrn.4805666.","DOI":"10.2139\/ssrn.4805666"}],"container-title":["International Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/ijod\/8992304","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/ijod\/8992304","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/ijod\/8992304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:18:33Z","timestamp":1772997513000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/ijod\/8992304"}},"subtitle":[],"editor":[{"given":"Murilo Baena","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/ijod\/8992304"],"URL":"https:\/\/doi.org\/10.1155\/ijod\/8992304","archive":["Portico"],"relation":{},"ISSN":["1687-8728","1687-8736"],"issn-type":[{"value":"1687-8728","type":"print"},{"value":"1687-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-05-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8992304"}}