{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T12:43:38Z","timestamp":1782823418769,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":180,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study compared oral health status and oral health\u2010related quality of life (OHRQoL) in women with polycystic ovary syndrome (PCOS) and age\u2010matched healthy controls and identified psychosocial and lifestyle determinants of oral health outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      A cross\u2010sectional study enrolled 72 women aged 18\u201345\u2009years (36 PCOS, 36 controls) from a gynecology outpatient department, with PCOS confirmed using 2003 Rotterdam criteria. Oral health was assessed using decayed, missing, and filled teeth (DMFT) and gingival bleeding score. OHRQoL, psychological stress, and lifestyle quality were measured using Oral Health Impact Profile (OHIP\u201014), four\u2010item Perceived Stress Scale (PSS\u20104), and eight\u2010item Health Practice Index (HPI\u20108), respectively. Analysis included Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      , Pearson chi\u2010square, Spearman correlation, logistic, and multiple linear regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both groups were sociodemographically comparable. PCOS women had significantly higher DMFT scores (median 4.00 vs. 1.50;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 &lt; 0.001), gingival bleeding scores (median 2.00 vs. 0.00;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 &lt; 0.001), and OHIP\u201014 total scores (median 8.50 vs. 2.50;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 &lt; 0.001) than controls. Six of seven OHIP\u201014 domains were significantly elevated; psychological discomfort and psychological disability showed the greatest differences. PSS\u20104 and HPI\u20108 scores did not differ significantly between groups (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.315 and\n                      <jats:italic>p<\/jats:italic>\n                      = 0.200, respectively). In an exploratory binary logistic regression, gingival bleeding (OR\u2009=\u20093.010), DMFT (OR\u2009=\u20092.187), and OHIP\u201014 total score (OR\u2009=\u20091.630) were independently associated with PCOS status (model accuracy 88.9%; to be interpreted cautiously, given sample size). PCOS disease status was the strongest variable associated with OHRQoL in the full\u2010sample model (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.384,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 &lt; 0.001; adjusted\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.589). Within PCOS subgroup, perceived psychological stress was the sole significant independent variable associated with OHRQoL (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.428,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.009).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Women with PCOS demonstrated significantly poorer oral health and reduced OHRQoL than healthy controls, with perceived psychological stress independently associated with OHRQoL within the PCOS subgroup. These associations are exploratory findings that require confirmation in larger longitudinal studies. Pending such confirmation, the findings support consideration of oral health assessment and psychosocial screening as components of multidisciplinary PCOS management, in alignment with Sustainable Development Goal 3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>Clinical Trials Registry of India: CTRI\/2025\/07\/090714<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/ijod\/9379119","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:43:32Z","timestamp":1782819812000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Oral\u2013Endocrine Interface: Clinical Oral Health Burden, Oral Health\u2010Related Quality of Life, and Psychosocial Determinants in Women With Polycystic Ovary Syndrome\u2014Evidence for Cross\u2010Disciplinary Prevention"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5082-8470","authenticated-orcid":false,"given":"Jeevan V.","family":"Sambasivan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0232-6226","authenticated-orcid":false,"given":"Deepak Kumar","family":"Singhal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9007-8092","authenticated-orcid":false,"given":"Nishu","family":"Singla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8749-0564","authenticated-orcid":false,"given":"Jishnu","family":"Pradeep","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8380-3889","authenticated-orcid":false,"given":"Aadil","family":"Abdulhameed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/NRENDO.2018.24"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-8-41"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.4103\/JHRS.JHRS_95_18"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.7759\/CUREUS.32351"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/09513590312331290268"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/FENDO.2023.1008675"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.FERTNSTERT.2010.07.1052"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.7759\/CUREUS.47169"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2741-2"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.1902\/JOP.2012.110588"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/JCM9051586"},{"key":"e_1_2_13_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/oral5030067"},{"key":"e_1_2_13_13_2","doi-asserted-by":"publisher","DOI":"10.14670\/HH-18-860"},{"key":"e_1_2_13_14_2","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.179405"},{"key":"e_1_2_13_15_2","volume-title":"Oral Health Surveys: Basic Methods","author":"World Health Organization","year":"2013"},{"key":"e_1_2_13_16_2","first-page":"3","article-title":"Development and Evaluation of the Oral Health Impact Profile","volume":"11","author":"Slade G. 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