{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:38:21Z","timestamp":1773005901528,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"vor","delay-in-days":180,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    This study aimed to investigate the tensile bond strength (TBS) and biofilm\u2010inhibitory antimicrobial properties of tissue conditioners combined with\n                    <jats:italic>Ocimum gratissimum<\/jats:italic>\n                    essential oil (EO) at varying concentrations.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Materials and Methods:<\/jats:bold>\n                    The original tissue conditioner was used as the control, while the experimental groups consisted of tissue conditioners incorporating\n                    <jats:italic>O. gratissimum<\/jats:italic>\n                    EO at concentrations of 1% and 2% (\n                    <jats:italic>v<\/jats:italic>\n                    \/\n                    <jats:italic>v<\/jats:italic>\n                    ) in the liquid component. The TBS between the tissue conditioner and denture base acrylic resin was measured using a universal testing machine. To evaluate biofilm\u2010inhibitory antimicrobial properties, cylindrical specimens infused with EO were prepared and incubated with\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    and\n                    <jats:italic>Streptococcus mutans<\/jats:italic>\n                    . The crystal violet assay was utilized to quantify microbial biofilm formation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    The incorporation of\n                    <jats:italic>O. gratissimum<\/jats:italic>\n                    EO into tissue conditioners significantly increased the TBS on day 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 &lt; 0.05) but showed no effect by day 7 post\u2010polymerization (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 &gt; 0.05). Additionally, tissue conditioners containing 1% EO exhibited biofilm\u2010inhibitory antimicrobial properties on day 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 &lt; 0.05), whereas those with 2% EO demonstrated biofilm\u2010inhibitory antimicrobial activity on both days 1 and 3 postinoculation (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 &lt; 0.05). By day 5 and 7, EO\u2010infused tissue conditioners no longer exhibited biofilm\u2010inhibitory antimicrobial properties (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009 &gt; 0.05).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Tissue conditioners infused with\n                    <jats:italic>O. gratissimum<\/jats:italic>\n                    EO effectively reduced the formation of biofilms by\n                    <jats:italic>C. albicans<\/jats:italic>\n                    and\n                    <jats:italic>S. mutans<\/jats:italic>\n                    in a dose\u2013dependent manner on days 1 and 3. As tissue conditioners are typically replaced every 3\u20137 days,\n                    <jats:italic>O. gratissimum<\/jats:italic>\n                    EO can be incorporated as an additive to lower the formation of biofilms by\n                    <jats:italic>C. albicans and S. mutans<\/jats:italic>\n                    without compromising the TBS of the tissue conditioner to denture base acrylic resin.\n                  <\/jats:p>","DOI":"10.1155\/ijod\/9994172","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T03:34:55Z","timestamp":1751254495000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of the Mechanical and Biofilm\u2010Inhibitory Antimicrobial Properties of a Dental Tissue Conditioner Incorporating\n                    <i>Ocimum Gratissimum<\/i>\n                    Essential Oil: An In Vitro 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Luc","family":"Truong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Van-Khoa","family":"Pham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natdhanai","family":"Chotprasert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2018.03.032"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/ccd.ccd_320_19"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.11607\/ijp.4553"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.2174\/1381612827666210224141559"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/1055665619882555"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1221"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2010.507605"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1590\/0103-6440201701266"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/62634"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpor.2016.03.006"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep41332"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5577760"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-5712(96)00050-4"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.12117"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2021.e08404"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24213864"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3913(13)60381-9"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.15171\/apb.2017.059"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.4103\/jispcd.JISPCD_187_22"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10024-1682"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00289-022-04414-9"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2024.07.014"},{"key":"e_1_2_10_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.GPP3-0051-2018"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens11040448"},{"key":"e_1_2_10_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00087-14"},{"key":"e_1_2_10_26_2","doi-asserted-by":"publisher","DOI":"10.1080\/20002297.2022.2144047"}],"container-title":["International 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