{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T16:24:34Z","timestamp":1770913474761,"version":"3.50.1"},"reference-count":56,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"vor","delay-in-days":42,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Pediatrics"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Human parechovirus (HPeV) is one of the major causes of viral meningitis in neonates. Following the COVID\u201019 pandemic, a resurgence of HPeV infections was reported worldwide. This exploratory case series is aimed at describing the symptoms of neonatal HPeV meningitis occurring after the lifting of large\u2010scale quarantine measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed eight neonates admitted between June 1, 2023, and September 30, 2023, with fever and HPeV detected in cerebrospinal fluid (CSF) using the FilmArray Meningitis\/Encephalitis Panel. Demographic variables, clinical presentation, laboratory data, respiratory support requirements, and treatment courses were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fever was the primary presenting symptom. Despite the absence of leukocytosis or pleocytosis, fever duration was prolonged (mean 4.3\u2009days). Four patients (50%) exhibited respiratory symptoms requiring high\u2010flow nasal cannula support. Hyponatremia occurred in two neonates without neurological manifestations\u2014an observation not commonly described in previous cohorts. No patients required invasive ventilation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This small, single\u2010center series suggests possible variations in neonatal HPeV presentation after the COVID\u201019 pandemic; however, findings are preliminary and hypothesis\u2010generating. Larger multicenter studies with subtype analysis and long\u2010term neurodevelopmental follow\u2010up are essential.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/ijpe\/9170564","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T15:35:56Z","timestamp":1770910556000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Differences in Clinical Manifestations of Human Parechovirus\u2013Related Meningitis in Neonates After the COVID\u201019 Pandemic: A Single\u2010Center Exploratory Study"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3550-5028","authenticated-orcid":false,"given":"Seong Wan","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3614-1238","authenticated-orcid":false,"given":"Hyun Joo","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7772-4686","authenticated-orcid":false,"given":"Yoong-A","family":"Suh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4765-9948","authenticated-orcid":false,"given":"Jang Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9101-3581","authenticated-orcid":false,"given":"Moon Sung","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7515-0554","authenticated-orcid":false,"given":"Seoheui","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,12]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000456"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/pix010"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/ped.13467"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piy079"},{"key":"e_1_2_11_5_2","first-page":"8","article-title":"Human Parechovirus Infection in Hong Kong Neonates, Infants, and Young Children: Abridged Secondary Publication","volume":"26","author":"Chan P. 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