{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T16:37:00Z","timestamp":1770136620676,"version":"3.49.0"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":32,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Aging Research"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Scientific and technological advances are emphasizing biomarker\u2010driven studies to diagnose, classify, and predict the pathogenesis of Alzheimer\u2019s disease (AD) and dementias (Ds) with the development of intelligent systems during these symptom\u2010free years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, the data of people over 65 who were diagnosed with AD\/D in 2020 were retrospectively scanned, and the data of 243,073 people identified were analyzed on a total of 32 variables, 6 of which were dependent variables and 26 were independent variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>It is understood from the logistic regression (LR) models that AD\/D is a multilayered and extraordinarily complex condition with biological, mental, and social dimensions rather than a single variable or parameter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>As a main result of the study, it is understood that instead of generalized diagnostic criteria, the appearance and boundaries of AD in society can be determined with specialized technology\u2010based smart systems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jare\/1010110","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T05:12:10Z","timestamp":1770095530000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A National Big Data Analysis on Alzheimer\u2019s and Other Dementias in T\u00fcrkiye"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4195-9149","authenticated-orcid":false,"given":"Talip","family":"Yi\u0307\u011fi\u0307t","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7276-8738","authenticated-orcid":false,"given":"Murat","family":"Di\u0307n\u00e7er","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6947-2821","authenticated-orcid":false,"given":"Naim","family":"Ata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0825-1851","authenticated-orcid":false,"given":"M. Mahir","family":"\u00dclg\u00fc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8104-6198","authenticated-orcid":false,"given":"\u015euayip","family":"Bi\u0307ri\u0307nci\u0307","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0116-5152","authenticated-orcid":false,"given":"M. Okan","family":"Ayvali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"e_1_2_12_1_2","unstructured":"World Health Organization Dementia https:\/\/www.who.int\/en\/news-room\/fact-sheets\/detail\/dementia."},{"key":"e_1_2_12_2_2","volume-title":"Memory Loss E-Book: A Practical Guide for Clinicians","author":"Budson A. E.","year":"2011"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2018.01.022"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0197-4580(98)00052-9"},{"key":"e_1_2_12_5_2","unstructured":"IhmeandGbd Results Global Burden of Disease (GBD) Study 2019 https:\/\/vizhub.healthdata.org\/gbd-results\/."},{"key":"e_1_2_12_6_2","unstructured":"National Institute on Aging Alzheimer\u2019s disease Fact Sheet https:\/\/www.nia.nih.gov\/health\/alzheimers-disease-fact-sheet."},{"key":"e_1_2_12_7_2","article-title":"The Humanistic and Economic Burden of Alzheimer\u2019s disease","volume":"11","author":"Monfared A. A.","year":"2022","journal-title":"Neurology and Therapy"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01605.x"},{"key":"e_1_2_12_9_2","article-title":"Instrumental Activities of Daily Living: A stepping-stone Towards Alzheimer\u2019s disease Diagnosis in Subjects with Mild Cognitive Impairment?","volume":"179","author":"Nygard L.","year":"2003","journal-title":"Acta Neurologica Scandinavica"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2004.01386.x"},{"key":"e_1_2_12_11_2","article-title":"Clinical Features of Alzheimer\u2019s Disease","volume":"249","author":"F\u00f6rstl H.","year":"1999","journal-title":"European Archives of Psychiatry and Clinical Neuroscience"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1995.tb06235.x"},{"key":"e_1_2_12_13_2","first-page":"417","article-title":"Effect of Alzheimer\u2019s disease on Communication Function","volume":"90","author":"Frank E. M.","year":"1994","journal-title":"Journal of the South Carolina Medical Association"},{"key":"e_1_2_12_14_2","article-title":"Midlife Cardiovascular Risk Factors and Risk of Dementia in Late Life","volume":"25","author":"Whitmer R. A.","year":"2005","journal-title":"Neurology"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30367-6"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.4782"},{"key":"e_1_2_12_17_2","article-title":"Comprehensive Review on Alzheimer\u2019s Disease: Causes and Treatment","volume":"25","author":"Brejiyeh Z.","year":"2020","journal-title":"Molecules"},{"key":"e_1_2_12_18_2","article-title":"Genetics of Familial and Sporadic Alzheimer\u2019s Disease","volume":"5","author":"Piaceri I.","year":"2013","journal-title":"Frontiers in Bioscience-Elite"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2018.10.009"},{"key":"e_1_2_12_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00269-y"},{"key":"e_1_2_12_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64012-3.00002-2"},{"key":"e_1_2_12_22_2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/B978-1-4377-0434-1.00009-8","volume-title":"Bradley\u2019s Neurology in Clinical Practice","author":"Murray E. D.","year":"2012"},{"key":"e_1_2_12_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-008853"},{"key":"e_1_2_12_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.05.020"},{"key":"e_1_2_12_25_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.112.118307"},{"key":"e_1_2_12_26_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10091809"},{"key":"e_1_2_12_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.64.2.234"},{"key":"e_1_2_12_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12327"},{"key":"e_1_2_12_29_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000200039"},{"key":"e_1_2_12_30_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.52387"},{"key":"e_1_2_12_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afab259"},{"key":"e_1_2_12_32_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042751"},{"key":"e_1_2_12_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-7568(21)00150-1"},{"key":"e_1_2_12_34_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000256368.57375.b7"},{"key":"e_1_2_12_35_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-137-3-200208060-00006"},{"key":"e_1_2_12_36_2","volume-title":"World Population Prospects 2022","author":"United Nations Department of Economic and Social Affairs","year":"2022"},{"key":"e_1_2_12_37_2","unstructured":"Turkish Statistical Institute Elderlies in Statistics 2021 https:\/\/data.tuik.gov.tr\/Bulten\/Index?p=Istatistiklerle-Yaslilar-2021-45636."},{"key":"e_1_2_12_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70072-2"},{"key":"e_1_2_12_39_2","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S544727"},{"key":"e_1_2_12_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70044-9"},{"key":"e_1_2_12_41_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1202753"},{"key":"e_1_2_12_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30028-0"},{"key":"e_1_2_12_43_2","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000513"},{"key":"e_1_2_12_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.05.006"},{"key":"e_1_2_12_45_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-221065"},{"key":"e_1_2_12_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2008.03.001"},{"key":"e_1_2_12_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2009.04.1234"},{"key":"e_1_2_12_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1099-1166(199906)14:6<481::aid-gps959>3.3.co;2-x"}],"container-title":["Journal of Aging Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jare\/1010110","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/jare\/1010110","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jare\/1010110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T05:12:13Z","timestamp":1770095533000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/jare\/1010110"}},"subtitle":[],"editor":[{"given":"Udhaya Kumar","family":"Siva Kumar","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/jare\/1010110"],"URL":"https:\/\/doi.org\/10.1155\/jare\/1010110","archive":["Portico"],"relation":{},"ISSN":["2090-2204","2090-2212"],"issn-type":[{"value":"2090-2204","type":"print"},{"value":"2090-2212","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-08-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1010110"}}