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Hyperglycemia was identified if fasting blood glucose was \u2265\u20095.6\u2009mmol\/L and\/or HbA1c \u2265\u20095.7%. Traditional Chinese medicine (TCM) body constitution was identified using China\u2032s national standard questionnaire, which is a scheme of preventive medicine derived from traditional medicine, including nine types of constitution. Participants may have a single or mixed type of TCM constitution. Cox proportional hazards models were used to assess the association between TCM constitution and the risk of new\u2010onset hyperglycemia. Stratified analyses were performed by age, sex, and low\u2010density lipoprotein cholesterol levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 8462 participants (37.46 \u00b1 9.42 years) included, 2376 (28.08%) individuals developed hyperglycemia during the median follow\u2010up of 27.93 months. Blood stasis constitution (sublingual vein distension, pigmentation; HR = 2.30, 95% CI 1.38\u20133.82) and those mixed with others (HR = 1.72, 95% CI 1.18\u20132.52), qi stagnation constitution (sentimental, depressed; HR = 1.91, 95% CI 1.13\u20133.24) and those mixed with others (HR = 1.87, 95% CI 1.24\u20132.83), phlegm\u2010dampness constitution (soft\/fat belly, loose and sticky stool; HR = 1.65, 95% CI 1.09\u20132.49), yang\u2010deficient constitution (cold\u2010sensitive; HR = 2.27, 95% CI 1.13\u20134.57), and damp\u2010heat constitution (halitosis, prone to acne; HR = 1.48, 95% CI 1.03\u20133.14) showed significant association with the increased risk of hyperglycemia in the general population. With the exception of yang\u2010deficient constitution (insufficient sample size), all other TCM constitutions showed significantly higher association with hyperglycemia in adults aged 18\u201344 years, but not in those aged \u2265\u200945 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Assessment based on a TCM constitutional questionnaire can serve as a risk indicator of the risk of hyperglycemia in the general population, particularly among young adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jdr\/5548887","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T07:13:46Z","timestamp":1790147626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["TCM Constitution and the Risk of Hyperglycemia in Young and Middle\u2010Aged Adults: A Retrospective 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