{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T06:03:11Z","timestamp":1784872991761,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":203,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes Research"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Obesity, impaired glucose tolerance, and diabetes significantly increase hypertension risk. Previous studies across various populations have linked the weight\u2010adjusted waist index (WWI)\u2014a key indicator for assessing obesity\u2014to hypertension. However, this relationship remains unclear specifically in non\u2010diabetic populations, particularly normoglycemic individuals. Focusing on normoglycemic Japanese adults, the present study explored the correlation of WWI with prehypertension or hypertension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data sourced from the program for medical screening at Murakami Memorial Hospital (Japan) were subjected to secondary analysis, which included 15,464 participants. To quantify the relationship of the WWI with prehypertension (pre\u2010HTN) or hypertension (HTN), multivariable logistic regression analyses were applied. Restricted cubic spline (RCS) models were further applied to evaluate the dose\u2013response relationship of WWI with the two outcomes. Subgroup analyses were also conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 15,453 normoglycemic Japanese adults, the mean WWI increased progressively across blood pressure categories (normal\u2009&lt;\u2009prehypertension\u2009&lt;\u2009hypertension). Following adjustment for key confounding variables, WWI was independently correlated with prehypertension (OR = 1.50, 95% CI: 1.39\u20131.61,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) and hypertension (OR = 1.74, 95% CI: 1.51\u20132.00,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Curve Fitting confirmed a linear, monotonic positive correlation of WWI with both outcomes (all\n                      <jats:italic>p<\/jats:italic>\n                      values for non\u2010linearity tests &gt;\u20090.05). Subgroup analyses revealed a stronger association between WWI and prehypertension in females, individuals without fatty liver disease, and current smokers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study demonstrated a positive linear correlation of WWI with both prehypertension and hypertension risk in normoglycemic Japanese individuals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jdr\/9044163","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:45:23Z","timestamp":1784871923000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prehypertension, Hypertension, and Their Association With Weight\u2010Adjusted Waist Index in Normoglycemic Japanese Adults: A Cross\u2010Sectional Study"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3238-2125","authenticated-orcid":false,"given":"Jing","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7657-9555","authenticated-orcid":false,"given":"Lu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9920-3201","authenticated-orcid":false,"given":"Fawang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9954-598X","authenticated-orcid":false,"given":"Shengfei","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4738-3311","authenticated-orcid":false,"given":"Yue","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9357-3475","authenticated-orcid":false,"given":"Qing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5746-7513","authenticated-orcid":false,"given":"Zhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"e_1_2_14_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32225-6"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32203-7"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-019-0244-2"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2560"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.305697"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-35073-4"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.16456"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2020.05.033"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1210669"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2024.06.006"},{"key":"e_1_2_14_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.00612"},{"key":"e_1_2_14_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.535039"},{"key":"e_1_2_14_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-018-0076-3"},{"key":"e_1_2_14_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12786"},{"key":"e_1_2_14_15_2","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.078980"},{"key":"e_1_2_14_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01526.x"},{"key":"e_1_2_14_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-019-0284-9"},{"key":"e_1_2_14_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.851338"},{"key":"e_1_2_14_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2024.1416836"},{"key":"e_1_2_14_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-025-02147-6"},{"key":"e_1_2_14_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000052314.95497.78"},{"key":"e_1_2_14_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303604"},{"key":"e_1_2_14_23_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R110.113175"},{"key":"e_1_2_14_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature21363"},{"key":"e_1_2_14_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06710-1"},{"key":"e_1_2_14_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(02)11911-8"},{"key":"e_1_2_14_27_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-177"},{"key":"e_1_2_14_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.12114"},{"key":"e_1_2_14_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hps001"},{"key":"e_1_2_14_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000066691.52789.BE"}],"container-title":["Journal of Diabetes Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jdr\/9044163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/jdr\/9044163","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jdr\/9044163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:45:24Z","timestamp":1784871924000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/jdr\/9044163"}},"subtitle":[],"editor":[{"given":"Hannah","family":"Wesley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/jdr\/9044163"],"URL":"https:\/\/doi.org\/10.1155\/jdr\/9044163","archive":["Portico"],"relation":{},"ISSN":["2314-6745","2314-6753"],"issn-type":[{"value":"2314-6745","type":"print"},{"value":"2314-6753","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9044163"}}