{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T18:30:09Z","timestamp":1786386609134,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:00:00Z","timestamp":1763769600000},"content-version":"vor","delay-in-days":325,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Nutrition and Metabolism"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Low estrogen levels affect bone mineral density and bone microarchitecture, increasing the risk of osteoporosis. This hormonal change can also contribute to the loss of strength, muscle mass, and physical performance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate associations between the components of sarcopenia and bone microarchitecture in postmenopausal women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted with 98 women \u2265 50\u2009years of age. Data were collected on sociodemographic, lifestyle, and clinical characteristics. Measurements were performed of height, body mass, calf circumference adjusted for BMI, grip strength, and physical performance using the Timed Up and Go test. The appendicular skeletal muscle mass index (ASMI) and bone mineral density were estimated by dual energy X\u2010ray absorptiometry. Bone microarchitecture was determined by the trabecular bone score. The association between ASMI and bone microarchitecture was tested using multivariate linear regression analysis with adjusted models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The participants were predominantly between 60.0 and 69.9\u2009years of age (62.3%), lived with a partner (51.0%), declared themselves to be non\u2010White (59.2%), had low or no education (67.3%), were sufficiently active (52.0%), and did not consume alcohol (87.8%) or smoke (94.9%). ASMI was associated with bone microarchitecture after the adjustment of the models (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.047; 95% CI: 0.009\u20130.084;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.015).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The positive association found between skeletal muscle mass and bone microarchitecture indicates that maintaining muscle mass may play a significant role in bone health among postmenopausal women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jnme\/3170619","type":"journal-article","created":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T09:37:46Z","timestamp":1763804266000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Muscle\u2013Bone Relationship: Positive Association Between Appendicular Skeletal Muscle Mass and Bone Microarchitecture in Postmenopausal Women"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4229-7968","authenticated-orcid":false,"given":"Camila Vilarinho","family":"Vidigal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1755-597X","authenticated-orcid":false,"given":"Patr\u00edcia Paula da Fonseca","family":"Grili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6752-0770","authenticated-orcid":false,"given":"Geise Ferreira da","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7471-1372","authenticated-orcid":false,"given":"Ben-Hur","family":"Albergaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7527-946X","authenticated-orcid":false,"given":"Luciane Daniele","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0783-5807","authenticated-orcid":false,"given":"Jos\u00e9 Luiz","family":"Marques-Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2266-6113","authenticated-orcid":false,"given":"Valdete Regina","family":"Guandalini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,22]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.4"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1530\/joe-23-0116"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-022-05167-2"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/bf01622200"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(02)08761-5"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2017.06.019"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2022.103887"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2013.07.001"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-024-01450-y"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acc.2019.07.010"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-016-0209-4"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.585644"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12567"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241814326"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-019-01266-8"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-018-4384-1"},{"key":"e_1_2_9_18_2","first-page":"1","article-title":"Influence of the Appendicular Skeletal Muscle Mass Index on the Bone Mineral Density of Postmenopausal Women","volume":"22","author":"Cruz G. F. d.","year":"2021","journal-title":"BMC Musculoskeletal Disorders"},{"key":"e_1_2_9_19_2","article-title":"Physical Status: The Use and Interpretation of Anthropometry","volume":"894","author":"WHO","year":"1995","journal-title":"WHO Technical Report Series"},{"key":"e_1_2_9_20_2","volume-title":"Anthropometric Standardization Reference Manual","author":"Lohman T. G.","year":"1988"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqab029"},{"key":"e_1_2_9_22_2","volume-title":"Official Positions Adult ISCD 2019","author":"The International Society For Clinical Densitometry","year":"2019"},{"key":"e_1_2_9_23_2","volume-title":"Clinical Assesment Recommendations","author":"MacDermid J.","year":"2015"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1991.tb01616.x"},{"key":"e_1_2_9_25_2","volume-title":"Self-Identification, ethnic-racial Identity and Heteroclassification","author":"Petruccelli J. L.","year":"2013"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2020.04.002"},{"key":"e_1_2_9_27_2","first-page":"5","article-title":"International Physical Activity Questionnaire (IPAQ): Validity and Reproducibility Study in Brazil","volume":"6","author":"Matsudo S.","year":"2001","journal-title":"Atividade F\u00edsica e Sa\u00fade"},{"key":"e_1_2_9_28_2","article-title":"WHO Guidelines on Physical Activity and Sedentary Behaviour, Web Annex, Evidence Profiles","volume":"535","author":"WHO","year":"2020","journal-title":"World Heal Organ"},{"key":"e_1_2_9_29_2","first-page":"37","article-title":"Ministry of Health","volume":"66","author":"Brazil","year":"2012","journal-title":"Resolution 466\/12 About Research Involving Human Beings"},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-018-0503-4"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells11223584"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13392"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2023.101370"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2017.01.035"}],"container-title":["Journal of Nutrition and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jnme\/3170619","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/jnme\/3170619","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jnme\/3170619","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T18:04:25Z","timestamp":1786385065000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/jnme\/3170619"}},"subtitle":[],"editor":[{"given":"Eric","family":"Gumpricht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/jnme\/3170619"],"URL":"https:\/\/doi.org\/10.1155\/jnme\/3170619","archive":["Portico"],"relation":{},"ISSN":["2090-0724","2090-0732"],"issn-type":[{"value":"2090-0724","type":"print"},{"value":"2090-0732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"3170619"}}