{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:55:20Z","timestamp":1786121720726,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":217,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Nutrition and Metabolism"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Anemia is one of the most widespread diseases, with one in four people affected by anemia worldwide. In sub\u2010Saharan Africa, anemia in preschool children is considered a severe public health problem. This study aimed to assess the prevalence of anemia and its associated factors among 6\u201359\u2010month\u2010old children in Ayder Comprehensive Specialized Referral Hospital, Tigray, Northern Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A hospital\u2010based cross\u2010sectional study was conducted among systematically selected 423 6\u201359\u2010month\u2010old children who were seeking service at Ayder Comprehensive Specialized Referral Hospital. Data were collected using a structured questionnaire. Four mL of venous blood from the finger was collected and analyzed using a Sysmex machine (model XP\u2010300). Anemia in children was defined as a hemoglobin level below 11\u2009g\/dL. Data were entered and analyzed using SPSS Version 21. Variables with a\n                      <jats:italic>p<\/jats:italic>\n                      value of &lt; 0.2 in the bivariable analysis were selected for multivariable logistic regression, and statistical significance was declared at\n                      <jats:italic>p<\/jats:italic>\n                      value &lt; 0.05 and CI of 95%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of anemia among children aged 6\u201359\u2009months was 57.1% (95% confidence interval: 52.2%\u201362.1%); of this magnitude, mild, moderate, and severe anemia was 27.1%, 20.9%, and 9.1%, respectively. Morphological, microcytic hypochromic anemia was the most common type of anemia. Children aged 6\u201323\u2009months (adjusted odds ratio\u2009=\u20092.374; 95% confidence interval: 1.428\u20133.945), stunting (adjusted odds ratio\u2009=\u20092.543; 95% confidence interval: 1.503\u20134.302), underweight (adjusted odds ratio\u2009=\u20096.660; 95% confidence interval: 3.046\u201314.566), and intestinal parasite infection (adjusted odds ratio\u2009=\u20092.803; 95% confidence interval: 1.242\u20136.322) were factors associated with anemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prevalence of anemia shows that it is a severe public health problem. Our findings underscore the need for nutrition counseling, deworming, growth monitoring, and promotion to minimize stunting, underweight, and intestinal parasite infection among children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jnme\/5114961","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T06:03:16Z","timestamp":1786082596000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Anemia and Its Associated Factors Among 6\u201359\u2010Month\u2010Old Children in Ayder Comprehensive Specialized Referral Hospital, Northern Ethiopia"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3298-1539","authenticated-orcid":false,"given":"Tigist Haile","family":"Gebrehiwot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4382-2886","authenticated-orcid":false,"given":"Abadi Hailay","family":"Atsbaha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1591-4554","authenticated-orcid":false,"given":"Shewit","family":"Engdashet Berhe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"e_1_2_11_1_2","volume-title":"Adjusting Hemoglobin Values in Program Surveys","author":"Nestel P.","year":"2002"},{"key":"e_1_2_11_2_2","article-title":"Haemoglobin Concentrations for the Diagnosis of Anaemia and Assessment of Severity","author":"WHO","year":"2011","journal-title":"Vitamin and Mineral Nutrition Information System. WHO\/NMH\/NHD\/MNM\/11.1"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/s1368980008002401"},{"key":"e_1_2_11_4_2","first-page":"150","article-title":"Prevalence of Anemia in Preschool and School Aged Children in Nigeria","volume":"3","author":"Osazuwa F.","year":"2010","journal-title":"Journal of Northern Sciences"},{"key":"e_1_2_11_5_2","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2471\/BLT.10.083568","article-title":"Spatial Heterogeneity of Haemoglobin Concentration in Preschool-Age Children in Sub-Saharan Africa","volume":"89","author":"Magalh\u00e3es R. J. S.","year":"2011","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_11_6_2","volume-title":"Ethiopia Demographic and Health Survey 2016","author":"Central Statistical Agency (CSA) [Ethiopia] and ICF","year":"2016"},{"key":"e_1_2_11_7_2","volume-title":"Worldwide Prevalence of Anaemia 1993\u20132005. WHO Global Database on Anaemia","author":"WHO","year":"2008"},{"key":"e_1_2_11_8_2","volume-title":"Anemia [Internet]","author":"Sanou D.","year":"2012"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0218961"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40795-016-0093-3"},{"key":"e_1_2_11_11_2","first-page":"35","article-title":"Prevalence of Anemia and Associated Factors Among Hospitalized Children Attending the University of Gondar Hospital, Northwest Ethiopia","volume":"30","author":"Enawgaw B.","year":"2019","journal-title":"EJIFCC"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.18203\/2349-3291.ijcp20170683"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.5581\/1516-8484.20110028"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.1499"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.4236\/oalib.1104351"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1017\/phn20062005"},{"key":"e_1_2_11_17_2","volume-title":"Nelson Text Book of Pediatrics","author":"Kliegman R. M.","year":"2016"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082455"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12878-015-0033-5"},{"key":"e_1_2_11_20_2","doi-asserted-by":"crossref","first-page":"499","DOI":"10.18203\/2349-3291.ijcp20180543","article-title":"Prevalence and Risk Factors of Anemia in Under Five-Year-Old Children in Children\u2019s Hospital","volume":"5","author":"Kanchana M.","year":"2018","journal-title":"International Journal of Contemporary Pediatrics"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0201806"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-015-0536-z"},{"key":"e_1_2_11_23_2","first-page":"646","article-title":"Prevalence of Anaemia and Associated Factors Among Children Below Five Years of Age in Cape Verde, West Africa","volume":"32","author":"Semedo R. M.","year":"2014","journal-title":"Journal of Health, Population and Nutrition"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155051"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.3329\/jdmc.v19i2.7084"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.12-0560"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/245870"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12604"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/928632"},{"key":"e_1_2_11_30_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001550"},{"key":"e_1_2_11_31_2","volume-title":"Advanced Nutrition and Human Metabolism","author":"Gropper S. S.","year":"2012"}],"container-title":["Journal of Nutrition and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jnme\/5114961","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/jnme\/5114961","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jnme\/5114961","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T06:03:19Z","timestamp":1786082599000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/jnme\/5114961"}},"subtitle":[],"editor":[{"given":"Suraiya","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/jnme\/5114961"],"URL":"https:\/\/doi.org\/10.1155\/jnme\/5114961","archive":["Portico"],"relation":{},"ISSN":["2090-0724","2090-0732"],"issn-type":[{"value":"2090-0724","type":"print"},{"value":"2090-0732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5114961"}}