{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:29:01Z","timestamp":1791048541264,"version":"4.1.0"},"reference-count":60,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":287,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010414","name":"Health Research Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010414","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["FP7\/2007-2013"],"award-info":[{"award-number":["FP7\/2007-2013"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014364","name":"National Children's Research Centre","doi-asserted-by":"publisher","award":["PRPG\/H\/18\/325"],"award-info":[{"award-number":["PRPG\/H\/18\/325"]}],"id":[{"id":"10.13039\/100014364","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Obesity"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/Objective<\/jats:title>\n                    <jats:p>Macrosomia is associated with overweight and obesity across the life course. Most research to date has been based on cross\u2010sectional analyses, and longitudinal investigations between macrosomia and developmental trajectories of growth throughout the first decade of life are lacking. This research aimed to examine associations between macrosomia and postnatal growth trajectories from birth to 10\u2009years of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects<\/jats:title>\n                    <jats:p>\n                      Children (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009337) from the ROLO longitudinal birth cohort, who were born to mothers with previous macrosomic delivery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Birthweight was recorded at delivery and dichotomised using the cut\u2010off criteria for macrosomia (birthweight \u2265 4\u2009kg and &lt; 4\u2009kg). Child weight, length\/height, body mass index (BMI) and waist circumference were measured at birth, 6\u2009months, 2, 5 and 10\u2009years of age. Postnatal growth trajectories were developed using these longitudinal measurements from birth up to 10\u2009years of age. Linear spline multilevel models were used to examine associations between macrosomia and postnatal trajectories with adjustment for confounders (maternal ethnicity, socioeconomic status, maternal age at delivery, maternal smoking in pregnancy, paternal BMI, adherence to gestational weight gain guidelines in pregnancy, sex of the child, original study group allocation, adherence to a special diet in pregnancy, maternal physical activity levels, metabolic complications in pregnancy and breastfeeding).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In this cohort, 53.7% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009181) had a birthweight \u2265 4\u2009kg. The median (IQR) early pregnancy BMI was 25.4 (23.1, 28.6) kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , and mothers were 33.1 (30.6, 35.3) years old at delivery. We found no strong evidence of associations between macrosomia and trajectories of childhood growth from birth to 10\u2009years of age. Significant findings in crude and adjusted models were close to the null and provide limited evidence for a meaningful association.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Macrosomia was associated with early, but not later, childhood growth trajectories. Associations were weak and varied according to definition and growth measurement. The lack of strong results indicates uncertain clinical relevance and warrant additional future research in a larger cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jobe\/8884369","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:37:17Z","timestamp":1760557037000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Macrosomia and Childhood Growth Trajectories From Birth to 10\u2009Years of Age: Findings From the ROLO Longitudinal Birth Cohort Study"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1146-2951","authenticated-orcid":false,"given":"Sophie","family":"Callanan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5195-0098","authenticated-orcid":false,"given":"Kaat","family":"Philippe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Delahunt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda M.","family":"O\u2019Keeffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4843-4265","authenticated-orcid":false,"given":"Kate N.","family":"O\u2019Neill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cara A.","family":"Yelverton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4916-4463","authenticated-orcid":false,"given":"Catherine M.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Twomey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciara M.","family":"McDonnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Declan","family":"Cody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3477-6494","authenticated-orcid":false,"given":"Fionnuala M.","family":"McAuliffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"key":"e_1_2_15_1_2","volume-title":"WHO European Regional Obesity Report 2022","author":"World Health Organisation","year":"2022"},{"key":"e_1_2_15_2_2","unstructured":"World Obesity Federation World Obesity Atlas 2023 https:\/\/data.worldobesity.org\/publications\/?cat=19."},{"key":"e_1_2_15_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyi309"},{"key":"e_1_2_15_4_2","doi-asserted-by":"publisher","DOI":"10.7570\/jomes20130"},{"key":"e_1_2_15_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-012-1136-2"},{"key":"e_1_2_15_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-015576"},{"key":"e_1_2_15_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-020-09456-0"},{"key":"e_1_2_15_8_2","doi-asserted-by":"publisher","DOI":"10.7555\/jbr.26.20120037"},{"key":"e_1_2_15_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-018039"},{"key":"e_1_2_15_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.02.053"},{"key":"e_1_2_15_11_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0222141"},{"key":"e_1_2_15_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12986-023-00759-8"},{"key":"e_1_2_15_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/77.3.726"},{"key":"e_1_2_15_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801211"},{"key":"e_1_2_15_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.08.042"},{"key":"e_1_2_15_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.02.010"},{"key":"e_1_2_15_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2047-6310.2012.00112.x"},{"key":"e_1_2_15_18_2","article-title":"Prenatal Exposure to Hyperglycemia and Child Growth Trajectories in the First Three Years of Life: A Prospective Birth Cohort","author":"Chen Y.","year":"2025","journal-title":"Research Square"},{"key":"e_1_2_15_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12982-024-00358-9"},{"key":"e_1_2_15_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckz232"},{"key":"e_1_2_15_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12201"},{"key":"e_1_2_15_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajcnut.2025.03.016"},{"key":"e_1_2_15_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/apa.17578"},{"key":"e_1_2_15_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.11835"},{"key":"e_1_2_15_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789x.2008.00475.x"},{"key":"e_1_2_15_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e5605"},{"key":"e_1_2_15_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2047-6310.2013.00216.x"},{"key":"e_1_2_15_28_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu8010007"},{"key":"e_1_2_15_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu6072946"},{"key":"e_1_2_15_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10389-016-0740-9"},{"key":"e_1_2_15_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12820"},{"key":"e_1_2_15_32_2","unstructured":"Grow Network GROW Customised Centile Calculators 2007."},{"key":"e_1_2_15_33_2","unstructured":"Institute of Medicine (US) and National Research Council (Us) Committee to Reexamine Iom Pregnancy Weight Guidelines Weight Gain During Pregnancy: Reexamining the Guidelines 2009."},{"key":"e_1_2_15_34_2","article-title":"Application of Multilevel Linear Spline Models for Analysis of Growth Trajectories in a Cohort With Repeat Antenatal and Postnatal Measures of Growth: A Prospective Cohort Study","volume":"13","author":"O\u2019Keeffe L. M.","year":"2023","journal-title":"British Medical Journal Open"},{"key":"e_1_2_15_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2020.10.078"},{"key":"e_1_2_15_36_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-023-04155-2"},{"key":"e_1_2_15_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2003.tb02471.x"},{"key":"e_1_2_15_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep14540"},{"key":"e_1_2_15_39_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.82.6.828"},{"key":"e_1_2_15_40_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.152.12.1225"},{"key":"e_1_2_15_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-021-01904-w"},{"key":"e_1_2_15_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20116"},{"key":"e_1_2_15_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwx271"},{"key":"e_1_2_15_44_2","doi-asserted-by":"publisher","DOI":"10.23750\/abm.v93i6.13823"},{"key":"e_1_2_15_45_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0212-16112011000500008"},{"key":"e_1_2_15_46_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-024-01671-4"},{"key":"e_1_2_15_47_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-17236-9"},{"key":"e_1_2_15_48_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.742551"},{"key":"e_1_2_15_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-021-00847-w"},{"key":"e_1_2_15_50_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.10.1.76"},{"key":"e_1_2_15_51_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2024-088641"},{"key":"e_1_2_15_52_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-023-05251-2"},{"key":"e_1_2_15_53_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4861523"},{"key":"e_1_2_15_54_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12976"},{"key":"e_1_2_15_55_2","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2018.1554041"},{"key":"e_1_2_15_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.06.001"},{"key":"e_1_2_15_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2017.03.003"},{"key":"e_1_2_15_58_2","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000002582"},{"key":"e_1_2_15_59_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-020-00336-6"},{"key":"e_1_2_15_60_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17782"}],"container-title":["Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jobe\/8884369","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/jobe\/8884369","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jobe\/8884369","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T11:08:28Z","timestamp":1774177708000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/jobe\/8884369"}},"subtitle":[],"editor":[{"given":"Claire","family":"Stocker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/jobe\/8884369"],"URL":"https:\/\/doi.org\/10.1155\/jobe\/8884369","archive":["Portico"],"relation":{},"ISSN":["2090-0708","2090-0716"],"issn-type":[{"value":"2090-0708","type":"print"},{"value":"2090-0716","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-01-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8884369"}}