{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:46:27Z","timestamp":1792046787944,"version":"4.4.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":286,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010096","name":"Southern Medical University","doi-asserted-by":"publisher","award":["2025CR009"],"award-info":[{"award-number":["2025CR009"]}],"id":[{"id":"10.13039\/501100010096","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171036"],"award-info":[{"award-number":["82171036"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515011735"],"award-info":[{"award-number":["2023A1515011735"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the long\u2010term efficacy of phacoemulsification combined with trabeculectomy (Phaco\u2010Trab) for advanced chronic primary angle\u2010closure glaucoma (PACG) with cataract.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with advanced chronic PACG coexisting with cataracts who underwent Phaco\u2010Trab were enrolled. The morphologic structures of filtering blebs, including characteristics under slit\u2010lamp examination, anterior segment optical coherence tomography (AS\u2010OCT), and in vivo confocal microscopy (IVCM), were used to evaluate the filtering function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 30 eyes from 27 patients were enrolled. The mean preoperative intraocular pressure (IOP) of 19.98\u2009\u00b1\u20096.48\u2009mmHg significantly decreased to 13.73\u2009\u00b1\u20092.35\u2009mmHg at year 3 (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.0001). A statistically significant decrease in postoperative IOP\u2010lowering medications was observed, but the number of drugs used increased annually (0.50\u2009\u00b1\u20090.82 at year 1, 1.00\u2009\u00b1\u20090.98 at year 2, and 1.47\u2009\u00b1\u20090.97 at year 3,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.0001). Following Phaco\u2010Trab, a high surgical qualified success rate was maintained over 3\u2009years (93.3% at year 1, 90.0% at year 2, and 80.0% at year 3,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.117). However, the complete success rate significantly decreased each year (70.0% at year 1, 36.7% at year 2, and 20.0% at year 3,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.0001), along with an increase in the rate of failure filtering blebs, reaching 46.7%, 83.3%, and 90.0% at each time point (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.0001). Overall, 46.7% (14\/30) of participants developed complications and required postoperative procedures after Phaco\u2010Trab, which were mainly induced by the trabeculectomy procedure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Phaco\u2010Trab can significantly lower IOP and reduce the use of IOP\u2010lowering medications for advanced chronic PACG with cataracts, but it is associated with a higher rate of complications and a higher failure rate of the filtering bleb.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/joph\/3442493","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:17:51Z","timestamp":1792045071000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Efficacy of Phacoemulsification Combined With Trabeculectomy for Advanced Chronic Primary Angle\u2010Closure Glaucoma With Cataract: A 3\u2010Year Retrospective Study"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8293-1111","authenticated-orcid":false,"given":"Chunxin","family":"Lai","sequence":"first","affiliation":[{"name":"Department of Ophthalmology the People\u2019s Hospital of Baiyun District  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0315-2179","authenticated-orcid":false,"given":"Baodi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology The Second Affiliated Hospital School of Medicine The Chinese University of Hong Kong, Shenzhen &amp; Longgang District People\u2019s Hospital of Shenzhen  Guangdong China"},{"name":"The First School of Clinical Medicine Southern Medical University  Guangzhou China  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