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Herein, we report preoperative diagnostic findings that reflect CXL outcomes and allow physicians to prognosticate treatment efficiency.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    In a medical centre, we retrospectively analysed pre\u2010 and postoperative data about 107 patients (112 eyes) treated with CXL from January 2018 to December 2022. Exclusion criteria were age below 16\u2009years, a corneal thickness below 400 microns, severe dry eye, other corneal diseases\/infections, re\u2010CXL, pregnancy and missing follow\u2010up examinations. All the subjects (79 males and 28 females) were followed for a minimum of 4 and a maximum of 40\u2009months. The study dataset was comprised of 796 cases of clinical assessment, pachymetry, visiometry, refractometry and topography examinations. With these data, we modelled maximum anterior keratometry (\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    ) and curvature power of the flat and steep meridians of the corneal anterior surface (\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>1<\/jats:sub>\n                    and\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>2<\/jats:sub>\n                    ).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Two years after the invasion, corneal curvature coefficients decreased progressively. Then, they remained stable for four months and rose afterwards. In the most accurate\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>1<\/jats:sub>\n                    ,\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>2<\/jats:sub>\n                    and\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    models, the proportion of mean absolute error to the range of values was 1.72, 3.66 and 2.37%, respectively. Pronounced corneal thinning, low best\u2010corrected visual acuity and high\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    levels predict unfavourable outcomes.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    The high accuracy of the models advocates for a personalised approach to candidate selection for CXL.\n                  <\/jats:p>","DOI":"10.1155\/joph\/3678453","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T07:35:08Z","timestamp":1751355308000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Individual Risk Assessment and Prognostication of Outcomes After Corneal Cross\u2010Linking"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7713-3333","authenticated-orcid":false,"given":"Y.","family":"Statsenko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6871-3046","authenticated-orcid":false,"given":"K.","family":"Liaonchyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1443-4902","authenticated-orcid":false,"given":"D.","family":"Morozova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5477-981X","authenticated-orcid":false,"given":"R.","family":"Voitetskii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9603-7785","authenticated-orcid":false,"given":"M.","family":"Pazniak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9741-4733","authenticated-orcid":false,"given":"E.","family":"Likhorad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7790-5636","authenticated-orcid":false,"given":"A.","family":"Pazniak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2031-3018","authenticated-orcid":false,"given":"P.","family":"Beliakouski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4936-5628","authenticated-orcid":false,"given":"D.","family":"Abelski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4462-8823","authenticated-orcid":false,"given":"D.","family":"Smetanina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2398-4730","authenticated-orcid":false,"given":"G.","family":"Simiyu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9551-1887","authenticated-orcid":false,"given":"K. 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