{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:03:00Z","timestamp":1777903380926,"version":"3.51.4"},"reference-count":135,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":317,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2021YFS0221"],"award-info":[{"award-number":["2021YFS0221"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2023YFS0179"],"award-info":[{"award-number":["2023YFS0179"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["2022HXFH032"],"award-info":[{"award-number":["2022HXFH032"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["ZYJC21058"],"award-info":[{"award-number":["ZYJC21058"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["2021-023"],"award-info":[{"award-number":["2021-023"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["2022-014"],"award-info":[{"award-number":["2022-014"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>The significance and contributions of corneal biomechanics in the study of chronic elevated intraocular pressure are multifaceted. Not only does it enhance our understanding of how chronic elevated intraocular pressure affects corneal structure and function, but it also offers new perspectives for the early diagnosis of glaucoma. Analysis of the cornea\u2019s biomechanical properties enables earlier identification of high\u2010risk glaucoma patients and potential development of personalized treatment plans, thereby improving treatment outcomes. Moreover, changes in corneal biomechanics can serve as a new metric for assessing glaucoma treatment effectiveness, providing precise clinical feedback. Continued research on the role of corneal biomechanics in chronic elevated intraocular pressure and glaucoma is crucial for improving the diagnosis, treatment, and prognosis. Understanding associations between these biomechanical changes and glaucoma development can elucidate disease mechanisms, enabling more effective treatment strategies and preventive measures. This review explores the latest research developments on corneal biomechanical changes associated with chronic elevated intraocular pressure and their impact on glaucoma management, highlighting the importance of these changes in clinical practice.<\/jats:p>","DOI":"10.1155\/joph\/8826306","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T10:31:14Z","timestamp":1763116274000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Corneal Biomechanical Changes Induced by Chronic Elevated Intraocular Pressure: Implications for Glaucoma Pathogenesis and Management"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1967-1029","authenticated-orcid":false,"given":"Mengzhen","family":"Xie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3500-3538","authenticated-orcid":false,"given":"Zhiyong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5193-428X","authenticated-orcid":false,"given":"Ke","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7653-658X","authenticated-orcid":false,"given":"Yingping","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0720-8616","authenticated-orcid":false,"given":"Jing","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.6.701"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.6.714"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.05.013"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1427.018"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2018.01.031"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(04)16257-0"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.2174\/1570159x16666180419121247"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-200101000-00011"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2004.11.030"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12923"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.953590"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2017.06.007"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2018-313493"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2019.0118"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-021-01437-W"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12938-022-01019-1"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12768"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-023-03215-6"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-023-01839-Z"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20200019"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.3109\/09273948.2015.1037459"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1080\/08164622.2021.1896335"},{"key":"e_1_2_10_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2022.108920"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2016-308432"},{"key":"e_1_2_10_25_2","doi-asserted-by":"publisher","DOI":"10.4103\/njcp.njcp_381_17"},{"key":"e_1_2_10_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000030248"},{"key":"e_1_2_10_27_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.595330"},{"key":"e_1_2_10_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000001901"},{"key":"e_1_2_10_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25020906"},{"key":"e_1_2_10_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0161-6420(94)31090-6"},{"key":"e_1_2_10_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0161-6420(96)30449-1"},{"key":"e_1_2_10_32_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22115708"},{"key":"e_1_2_10_33_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.64.4.3"},{"key":"e_1_2_10_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2020.108137"},{"key":"e_1_2_10_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2023.109570"},{"key":"e_1_2_10_36_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24043555"},{"key":"e_1_2_10_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2023.109476"},{"key":"e_1_2_10_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2023.109510"},{"key":"e_1_2_10_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2023.101192"},{"key":"e_1_2_10_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.14027"},{"key":"e_1_2_10_41_2","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2021.1945109"},{"key":"e_1_2_10_42_2","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2023.2206067"},{"key":"e_1_2_10_43_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.874828"},{"key":"e_1_2_10_44_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.61.10.38"},{"key":"e_1_2_10_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2018.05.004"},{"key":"e_1_2_10_46_2","doi-asserted-by":"publisher","DOI":"10.1097\/j.jcrs.0000000000000543"},{"key":"e_1_2_10_47_2","doi-asserted-by":"publisher","DOI":"10.18063\/ijb.v8i2.552"},{"key":"e_1_2_10_48_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00066"},{"key":"e_1_2_10_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2015.07.001"},{"key":"e_1_2_10_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.04.013"},{"key":"e_1_2_10_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3896"},{"key":"e_1_2_10_52_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsta.2018.0079"},{"key":"e_1_2_10_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.03.026"},{"key":"e_1_2_10_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.11.015"},{"key":"e_1_2_10_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2023.109446"},{"key":"e_1_2_10_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2020.108188"},{"key":"e_1_2_10_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2020.108202"},{"key":"e_1_2_10_58_2","first-page":"623","article-title":"Alterations in Proteome of Human Sclera Associated With Primary Open-Angle Glaucoma Involve Proteins Participating in Regulation of the Extracellular Matrix","volume":"26","author":"Iomdina E. N.","year":"2020","journal-title":"Molecular Vision"},{"key":"e_1_2_10_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2019.100773"},{"key":"e_1_2_10_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120735"},{"key":"e_1_2_10_61_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2020.0708"},{"key":"e_1_2_10_62_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00682"},{"key":"e_1_2_10_63_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10237-020-01333-4"},{"key":"e_1_2_10_64_2","doi-asserted-by":"publisher","DOI":"10.1115\/1.4049157"},{"key":"e_1_2_10_65_2","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering11100996"},{"key":"e_1_2_10_66_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.701997"},{"key":"e_1_2_10_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2018.05.042"},{"key":"e_1_2_10_68_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2005.0034"},{"key":"e_1_2_10_69_2","doi-asserted-by":"publisher","DOI":"10.1109\/tmi.2009.2021471"},{"key":"e_1_2_10_70_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/496382"},{"key":"e_1_2_10_71_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-25535"},{"key":"e_1_2_10_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2020.11.021"},{"key":"e_1_2_10_73_2","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.11.6.10"},{"key":"e_1_2_10_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.10.044"},{"key":"e_1_2_10_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.11.051"},{"key":"e_1_2_10_76_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1321"},{"key":"e_1_2_10_77_2","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering10010120"},{"key":"e_1_2_10_78_2","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000019126"},{"key":"e_1_2_10_79_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12672"},{"key":"e_1_2_10_80_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000000133"},{"key":"e_1_2_10_81_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.1018653"},{"key":"e_1_2_10_82_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00105"},{"key":"e_1_2_10_83_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-27346-W"},{"key":"e_1_2_10_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2021.108508"},{"key":"e_1_2_10_85_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209480"},{"key":"e_1_2_10_86_2","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.9.7.4"},{"key":"e_1_2_10_87_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-11387"},{"key":"e_1_2_10_88_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-8281"},{"key":"e_1_2_10_89_2","doi-asserted-by":"publisher","DOI":"10.1364\/oe.20.009197"},{"key":"e_1_2_10_90_2","doi-asserted-by":"publisher","DOI":"10.1364\/ol.42.002738"},{"key":"e_1_2_10_91_2","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.12.3.25"},{"key":"e_1_2_10_92_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1556"},{"key":"e_1_2_10_93_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0b013e31815c3a93"},{"key":"e_1_2_10_94_2","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20170050"},{"key":"e_1_2_10_95_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-018-1011-2"},{"key":"e_1_2_10_96_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000001819"},{"key":"e_1_2_10_97_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-90588-7"},{"key":"e_1_2_10_98_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-021-05212-1"},{"key":"e_1_2_10_99_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2019.11.017"},{"key":"e_1_2_10_100_2","doi-asserted-by":"publisher","DOI":"10.2147\/opth.s93725"},{"key":"e_1_2_10_101_2","doi-asserted-by":"publisher","DOI":"10.2147\/opth.s498422"},{"key":"e_1_2_10_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.12.007"},{"key":"e_1_2_10_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2019.07.023"},{"key":"e_1_2_10_104_2","doi-asserted-by":"publisher","DOI":"10.1097\/icu.0000000000000130"},{"key":"e_1_2_10_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogla.2022.03.006"},{"key":"e_1_2_10_106_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.12.018"},{"key":"e_1_2_10_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.01.032"},{"key":"e_1_2_10_108_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2012.164"},{"key":"e_1_2_10_109_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2008.01370.x"},{"key":"e_1_2_10_110_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000001625"},{"key":"e_1_2_10_111_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2022.11.009"},{"key":"e_1_2_10_112_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-16926"},{"key":"e_1_2_10_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2015.01.007"},{"key":"e_1_2_10_114_2","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2022.2059809"},{"key":"e_1_2_10_115_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.ijo_822_23"},{"key":"e_1_2_10_116_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000001268"},{"key":"e_1_2_10_117_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.751628"},{"key":"e_1_2_10_118_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2008.02.006"},{"key":"e_1_2_10_119_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597x-20071001-11"},{"key":"e_1_2_10_120_2","doi-asserted-by":"publisher","DOI":"10.1097\/cm9.0000000000001399"},{"key":"e_1_2_10_121_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0241296"},{"key":"e_1_2_10_122_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.ijo_1550_19"},{"key":"e_1_2_10_123_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.61.4.19"},{"key":"e_1_2_10_124_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2010.06.018"},{"key":"e_1_2_10_125_2","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.10.9.36"},{"key":"e_1_2_10_126_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000002170"},{"key":"e_1_2_10_127_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2022.06.014"},{"key":"e_1_2_10_128_2","doi-asserted-by":"publisher","DOI":"10.22608\/APO.2018334"},{"key":"e_1_2_10_129_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2023.1174419"},{"key":"e_1_2_10_130_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14115"},{"key":"e_1_2_10_131_2","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.9.12.25"},{"key":"e_1_2_10_132_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6927"},{"key":"e_1_2_10_133_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.47"},{"key":"e_1_2_10_134_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1342"},{"key":"e_1_2_10_135_2","doi-asserted-by":"publisher","DOI":"10.3390\/vision7020036"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/joph\/8826306","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/joph\/8826306","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/joph\/8826306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:57:49Z","timestamp":1777636669000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/joph\/8826306"}},"subtitle":[],"editor":[{"given":"Shweta","family":"Negi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":135,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/joph\/8826306"],"URL":"https:\/\/doi.org\/10.1155\/joph\/8826306","archive":["Portico"],"relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8826306"}}