{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T06:41:40Z","timestamp":1783406500987,"version":"3.54.6"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":332,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Antirabies vaccine postexposure prophylaxis (PEP) is effective in preventing rabies when administered promptly and in full. This study assessed factors associated with antirabies PEP full\u2010dose completion among patients attending Nyagatare District Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A facility\u2010based cross\u2010sectional study was conducted using data from patients who sought antirabies PEP at the hospital\u2019s emergency department in 2022. Patient files and registers were reviewed, and data were analyzed in STATA. Logistic regression was performed to identify factors associated with vaccine completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 472 participants, 50.0% were under 16\u2009years, 58.9% were male, and 63.6% lived in rural areas. Most (90.9%) had health insurance, 51.7% received PEP during the dry season, 11.0% received the antitetanus vaccine, and 82.2% had WHO wound Category II. Only 26.5% completed the full vaccination schedule, 16.1% missed appointments, and 57.4% dropped out before completion. Health insurance significantly increased the odds of completing PEP (AOR\u2009=\u20092.19,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.032). Age, sex, and wound characteristics were not significantly associated with ARV full\u2010dose completion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Compliance with the full antirabies vaccine course was low, with only a quarter of patients completing all five doses. Improving completion requires targeted interventions such as reminder systems, community education, provider counseling, and financial support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jotm\/2709448","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T08:30:21Z","timestamp":1764405021000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Epidemiology and Determinants of Antirabies Vaccine Full\u2010Dose Completion Among Patients Attending the Nyagatare District Hospital, Rwanda: A Facility\u2010Based Cross\u2010Sectional Study"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9032-1709","authenticated-orcid":false,"given":"Jean Paul","family":"Hategekimana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Manishimwe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetan","family":"Gatete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Nshimiyimana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmerance H.","family":"Gihozo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allain P.","family":"Mutabazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patience","family":"Karemera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Muturagara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddy K.","family":"Ndayambaje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"e_1_2_18_1_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-066587"},{"key":"e_1_2_18_2_2","volume-title":"WHO Expert Consultation on Rabies: Third Report","author":"World Health Organization","year":"2018"},{"key":"e_1_2_18_3_2","volume-title":"Third Report. WHO Technical Report Series, No. 1012","author":"WHO Expert Consultation on Rabies","year":"2018"},{"key":"e_1_2_18_4_2","unstructured":"Zero by 30 The Global Strategic Plan to Prevent Human Deaths from Dog-Transmitted Rabies by 2030."},{"key":"e_1_2_18_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lansea.2023.100258"},{"key":"e_1_2_18_6_2","doi-asserted-by":"publisher","DOI":"10.18502\/ijph.v51i5.9412"},{"key":"e_1_2_18_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13149-013-0312-y"},{"key":"e_1_2_18_8_2","doi-asserted-by":"publisher","DOI":"10.1017\/s0950268824000049"},{"key":"e_1_2_18_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210044"},{"key":"e_1_2_18_10_2","doi-asserted-by":"publisher","DOI":"10.4314\/rjmhs.v6i1.8"},{"key":"e_1_2_18_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9040309"},{"key":"e_1_2_18_12_2","unstructured":"National Institute of Statistics of Rwanda (NISR) M of F and EP (MINECOFIN) R Nyagatare District Profile 2012 Rwanda Fourth Popul Hous Census."},{"key":"e_1_2_18_13_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2019.33.112.16624"},{"key":"e_1_2_18_14_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.14229"},{"key":"e_1_2_18_15_2","doi-asserted-by":"publisher","DOI":"10.26611\/10111132"},{"key":"e_1_2_18_16_2","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_497_22"},{"key":"e_1_2_18_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/2292550318767924"},{"key":"e_1_2_18_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3928-0"},{"key":"e_1_2_18_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.878886"},{"key":"e_1_2_18_20_2","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_592_19"},{"key":"e_1_2_18_21_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0252058"},{"key":"e_1_2_18_22_2","doi-asserted-by":"publisher","DOI":"10.5455\/2394-6040.ijcmph20150517"},{"key":"e_1_2_18_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007248"},{"key":"e_1_2_18_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.08.086"}],"container-title":["Journal of Tropical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jotm\/2709448","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/jotm\/2709448","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/jotm\/2709448","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:56:06Z","timestamp":1777636566000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/jotm\/2709448"}},"subtitle":[],"editor":[{"given":"Lipi","family":"Buch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/jotm\/2709448"],"URL":"https:\/\/doi.org\/10.1155\/jotm\/2709448","archive":["Portico"],"relation":{},"ISSN":["1687-9686","1687-9694"],"issn-type":[{"value":"1687-9686","type":"print"},{"value":"1687-9694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-10-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2709448"}}