{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:30:48Z","timestamp":1773927048735,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:00:00Z","timestamp":1770508800000},"content-version":"vor","delay-in-days":38,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Synthetic insecticides face challenges, such as resistance, environmental damage, and harm to nontarget species, highlighting the need for alternative methods. Medicinal plants, along with their bioactive compounds, offer a promising solution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      This study investigated the efficacy of methanol extracts derived from traditionally used Ethiopian medicinal plants against\n                      <jats:italic>Anopheles arabiensis<\/jats:italic>\n                      and\n                      <jats:italic>Aedes aegypti.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Materials<\/jats:title>\n                    <jats:p>Methanol extracts (80%) of the crude plant extracts were tested on the larvae and eggs of both mosquito species at concentrations ranging from 250 to 2000\u2009ppm. Larval mortality was recorded after 24\u2009h of exposure, while egg hatchability was assessed after 72\u2009h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Millettia ferruginea<\/jats:italic>\n                      exhibited the highest larvicidal activity against\n                      <jats:italic>Anopheles arabiensis<\/jats:italic>\n                      (LC\n                      <jats:sub>50<\/jats:sub>\n                      \u2009=\u2009461.7\u2009ppm, LC\n                      <jats:sub>90<\/jats:sub>\n                      \u2009=\u20091746.8\u2009ppm), achieving 90% inhibition of egg hatching at 2000\u2009ppm.\n                      <jats:italic>Momordica foetida<\/jats:italic>\n                      resulted in 85% mortality in second\u2010instar larvae and 80% mortality in early fourth\u2010instar larvae of\n                      <jats:italic>Anopheles arabiensis<\/jats:italic>\n                      at 2000\u2009ppm.\n                      <jats:italic>Securidaca longepedunculata<\/jats:italic>\n                      demonstrated 87% larval mortality and 92% egg hatching inhibition in\n                      <jats:italic>Aedes aegypti<\/jats:italic>\n                      at 2000\u2009ppm. ANOVA result shows that mortality rates varied significantly across concentrations (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Millettia ferruginea<\/jats:italic>\n                      ,\n                      <jats:italic>Momordica foetida<\/jats:italic>\n                      , and\n                      <jats:italic>Securidaca longepedunculata<\/jats:italic>\n                      are promising botanical insecticides. Future studies should focus on isolating active compounds to ensure environmental safety and effectiveness. These findings highlight the potential of indigenous plants for insect management and underscore the importance of traditional knowledge in the development of novel insecticides.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/jotm\/4047678","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T05:29:01Z","timestamp":1770614941000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Larvicidal and Ovicidal Effects of Methanol Extracts From Selected Ethiopian Medicinal Plants Against\n                    <i>Anopheles arabiensis<\/i>\n                    and\n                    <i>Aedes aegypti<\/i>"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6285-7566","authenticated-orcid":false,"given":"Lensa","family":"Tesfaye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6460-3850","authenticated-orcid":false,"given":"Esayas","family":"Aklilu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2166-6461","authenticated-orcid":false,"given":"Ketema","family":"Tolossa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2592-8684","authenticated-orcid":false,"given":"Abebe","family":"Animut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,8]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-7-382"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2008.08.030"},{"key":"e_1_2_12_3_2","first-page":"1","article-title":"Species Diversity and Distribution of Anopheles Mosquitoes in Bure District, Northwestern Ethiopia","volume":"6","author":"Tilahun A.","year":"2020","journal-title":"Heliyon"},{"key":"e_1_2_12_4_2","unstructured":"Who Disease Outbreak News; 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