{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:55:30Z","timestamp":1782849330490,"version":"3.54.5"},"reference-count":69,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":180,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    The emergence of multidrug\u2010resistant (MDR)\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    in healthcare settings poses a critical global health challenge, intensified by limited therapeutic options and the environmental spread of pathogens through hospital waste. This study addresses the urgent need for alternative strategies by investigating the phylogenetic profile and antimicrobial resistance of\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    isolated from hospital dry waste in Saidu Sharif, Pakistan, while evaluating the antibacterial and antioxidant potential of nine ethnomedicinal herbs. The isolate, identified via 16S rRNA sequencing, exhibited 99% homology to the MDR strain\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    610D6 reported from China, underscoring potential transboundary resistance dissemination. Antibiotic susceptibility testing revealed resistance to 14 of 21 tested agents, with retained efficacy only for imipenem, cefoperazone\/sulbactam (25\u2010mm inhibition zones), and fosfomycin (24\u2009mm). Ethanol extracts of\n                    <jats:italic>Punica granatum<\/jats:italic>\n                    ,\n                    <jats:italic>Myrtus communis<\/jats:italic>\n                    , and\n                    <jats:italic>Olea ferruginea<\/jats:italic>\n                    demonstrated remarkable antipseudomonad activity (26\u2010mm, 26\u2010mm, and 25\u2010mm zone of inhibitions, respectively) and potent antioxidant properties (97.57%, 95.55%, and 96.85% DPPH scavenging). Notably, solvent polarity significantly influenced extraction yields and bioactivity, with ethanol. This work highlights the therapeutic promise of plant\u2010derived compounds against MDR pathogens while encouraging for One Health approaches to mitigate antibiotic resistance.\n                  <\/jats:p>","DOI":"10.1155\/jotm\/4668333","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:31:13Z","timestamp":1782847873000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Phylogenetic Analysis and In Vitro Antimicrobial Potential of Some Herbal Extracts Against Multidrug\u2010Resistant\n                    <i>Pseudomonas aeruginosa<\/i>\n                    Isolate Recovered From Hospital Wastes"],"prefix":"10.1155","volume":"2026","author":[{"given":"Muhammad Nazir","family":"Uddin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taha","family":"Fatima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mian Syed Ali","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ishaq","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4463-3750","authenticated-orcid":false,"given":"Wajid","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeedah Musaed","family":"Almutairi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Soliman Elshikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6851-2884","authenticated-orcid":false,"given":"Farman","family":"Ullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iftikhar","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Shahzad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Taj-ud-Din","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"e_1_2_11_1_2","volume-title":"Biomedical Waste Analysis","author":"Bhatt K.","year":"2024"},{"key":"e_1_2_11_2_2","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.5897\/AJB2009.000-9473","article-title":"Microbiological Effects of Hospital Wastes on the Environment","volume":"8","author":"Oyeleke S. 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