{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:01:17Z","timestamp":1777903277107,"version":"3.51.4"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"vor","delay-in-days":222,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010679","name":"Pasteur Institute of Iran","doi-asserted-by":"publisher","award":["1555"],"award-info":[{"award-number":["1555"]}],"id":[{"id":"10.13039\/501100010679","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013822","name":"Kurdistan University Of Medical Sciences","doi-asserted-by":"publisher","award":["IR.MUK.REC.1397\/69"],"award-info":[{"award-number":["IR.MUK.REC.1397\/69"]}],"id":[{"id":"10.13039\/501100013822","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Q fever is a zoonotic bacterial infection with worldwide distribution. Based on seroepidemiology studies among the human population and also serological and molecular surveys of animals, Q fever is an endemic disease in Iran. However, the status of acute Q fever in many parts of Iran is still unknown. This study aimed to investigate acute Q fever among high\u2010risk patients with fever and pneumonia symptoms in Western Iran.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    In this survey, 96 patients were included in the study in Kurdistan Province who had symptoms of suspected pneumonia or acute Q fever and epidemiological evidence for the risk of Q fever. From each individual, paired acute and convalescent serum samples were taken, and the elevation of the phase II IgG antibody titer against\n                    <jats:italic>Coxiella burnetii<\/jats:italic>\n                    was traced by ELISA. Also, molecular detection of\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    was done in acute blood samples by real\u2010time PCR.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Seven patients (7.3%) were diagnosed with acute Q fever who had seroconversion and a four\u2010fold rise in the phase II IgG antibody titer against\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    in their paired sera samples. Also, 22 of 89 (24.7%) individuals with a negative result for acute Q fever had a previous history of exposure to\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    . There was a significant relationship between sheep husbandry and a previous history of exposure to\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.04). All molecular tests were negative.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    The results of this study showed that there are cases of acute Q fever in Western Iran, but it is not considered by the healthcare system or clinicians.\n                  <\/jats:p>","DOI":"10.1155\/jotm\/6685577","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T04:19:41Z","timestamp":1754972381000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Acute Q Fever Among High\u2010Risk Patients With Fever and Pneumonia Symptoms in Western 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