{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:41:17Z","timestamp":1773002477106,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Metal-Based Drugs"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>The synthesis, spectroscopic characterization and <jats:italic>in vitro<\/jats:italic> antitumour activity of two triorganotin\ncompounds, triphenyltin ortho\u2010aminophenylthiolate (<jats:bold>1<\/jats:bold>) and triphenyltin 2\u2010pyridylthiolate,\ncompound (<jats:bold>2<\/jats:bold>) are reported. The structure of <jats:bold>1<\/jats:bold> is confirmed by X\u2010ray diffraction, with the tin atom in\na distorted tetrahedral geometry because of monodentate coordination, as a thiolate (Sn\u2010S\n2.431(2) \u00c5), of the ortho\u2010aminophenylthiolate ligand. The <jats:italic>in vitro<\/jats:italic> antitumour activities of <jats:bold>1<\/jats:bold> and <jats:bold>2<\/jats:bold>,\nagainst a number of cell lines, are comparable to those exhibited by methotrexate and doxorubicin,\nand higher than those of carboplatin and cisplatin.<\/jats:p>","DOI":"10.1155\/mbd.1996.75","type":"journal-article","created":{"date-parts":[[2007,3,14]],"date-time":"2007-03-14T12:33:53Z","timestamp":1173875633000},"page":"75-78","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Triphenyltin Ortho\u2010Aminophenyl\u2010 and 2\u2010Pyridyl\u2010Thiolates:Synthesis and <i>In Vitro<\/i> Antitumour Activity"],"prefix":"10.1155","volume":"3","author":[{"given":"Marcel","family":"Gielen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdeslam","family":"Bouhdid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward R. T.","family":"Tiekink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dick","family":"de Vos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolph","family":"Willem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1996,2,27]]},"container-title":["Metal-Based Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/1996\/538128.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/MBD.1996.75","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T20:25:47Z","timestamp":1723148747000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/MBD.1996.75"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1155\/MBD.1996.75"],"URL":"https:\/\/doi.org\/10.1155\/mbd.1996.75","archive":["Portico"],"relation":{},"ISSN":["0793-0291","1687-5486"],"issn-type":[{"value":"0793-0291","type":"print"},{"value":"1687-5486","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]},"assertion":[{"value":"1996-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-02-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-02-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}