{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:41:16Z","timestamp":1773002476409,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1997,3,7]],"date-time":"1997-03-07T00:00:00Z","timestamp":857692800000},"content-version":"vor","delay-in-days":65,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Metal-Based Drugs"],"published-print":{"date-parts":[[1997,1]]},"abstract":"<jats:p>X\u2010ray diffraction studies reveal the structure of <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mbd415892-math-0001.png\" xlink:title=\"urn:x-wiley:07930291:media:mbd415892:mbd415892-math-0001\"\/>, <jats:bold>1<\/jats:bold>, to conform to the common motif found for <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mbd415892-math-0002.png\" xlink:title=\"urn:x-wiley:07930291:media:mbd415892:mbd415892-math-0002\"\/> compounds. The dimer features a central Bu<jats:sub>4<\/jats:sub>Sn<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> unit (two\u2010fold symmetry) with the two Bu<jats:sub>2<\/jats:sub>Sn groups being linked via bridging oxygen atoms, each of which also carries an exocyclic Bu<jats:sub>2<\/jats:sub>Sn moiety. The two pairs of exo\u2010 and endo\u2010cyclic tin atoms are each linked via an almost symmetrically bridging carboxylate ligand and the two remaining ligands coordinate an exocyclic tin atom only, in the monodentate mode. The <jats:italic>in vitro<\/jats:italic> anti\u2010tumour activity of <jats:bold>1<\/jats:bold>, determined against a variety of cell lines, is compared with those of the corresponding 2\u2010methylcarboranylacetate, derivative <jats:bold>2<\/jats:bold>, and with clinically used compounds.<\/jats:p>","DOI":"10.1155\/mbd.1997.75","type":"journal-article","created":{"date-parts":[[2007,3,14]],"date-time":"2007-03-14T12:33:53Z","timestamp":1173875633000},"page":"75-80","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["X\u2010Ray Structure and <i>In Vitro<\/i> Anti\u2010Tumoural Activity of the Dimeric Bis[(2\u2010Phenyl\u20101,2\u2010Dicarba\u2010<i>Closo<\/i>\u2010Dodecaborane\u20101\u2010Carboxylato)\u2010Di\u2010n\u2010Butyltin] Oxide"],"prefix":"10.1155","volume":"4","author":[{"given":"Edward R. T.","family":"Tiekink","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel","family":"Gielen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdeslam","family":"Bouhdid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolph","family":"Willem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir I.","family":"Bregadze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia V.","family":"Ermanson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey A.","family":"Glazun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1997,3,7]]},"container-title":["Metal-Based Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/1997\/415892.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/MBD.1997.75","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T18:39:22Z","timestamp":1719945562000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/MBD.1997.75"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["10.1155\/MBD.1997.75"],"URL":"https:\/\/doi.org\/10.1155\/mbd.1997.75","archive":["Portico"],"relation":{},"ISSN":["0793-0291","1687-5486"],"issn-type":[{"value":"0793-0291","type":"print"},{"value":"1687-5486","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,1]]},"assertion":[{"value":"1997-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-03-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-03-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}