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Consequently, the dysregulation of lipid homeostasis is recognized as a significant contributor to metabolic diseases. Given the limitations of current strategies for regulating lipid metabolism, it is essential to explore innovative approaches to modulate lipid homeostasis to effectively address diseases associated with its dysregulation. Inflammation plays a critical role in the regulation of lipid metabolism, acting through various pathways and mechanisms that influence both lipid synthesis and degradation. The involvement of Interleukin\u201017 (IL\u201017) in inflammatory responses is particularly noteworthy, as recent studies have highlighted its impact on lipid metabolism, particularly in the context of obesity and metabolic disorders. This review critically examines the IL\u201017 signaling pathway, elucidates the mechanisms by which IL\u201017 affects lipid metabolism, and explores the therapeutic potential of targeting IL\u201017 in the treatment of disorders related to lipid homeostasis. This review underscores the promise of targeting IL\u201017 signaling pathways as a therapeutic strategy for addressing the dysregulation in lipid homeostasis.<\/jats:p>","DOI":"10.1155\/mi\/7063696","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:50:16Z","timestamp":1780051816000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Targeting IL\u201017 Presents a Promising Strategy for Treating Diseases Related to the Dysregulation of Lipid 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