{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:40:06Z","timestamp":1787161206252,"version":"build-2736575974"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mediators of Inflammation"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p>\n                    Acne vulgaris is one of the common dermatological\ndiseases and its pathogenesis is multifactorial. In this study, we\naim to determine the effects of oxidative stress in acne vulgaris.\nForty\u2010three consecutive acne\npatients and 46 controls were enrolled. The parameters of\noxidative stress such as catalase (CAT), glucose\u20106\u2010phosphate\ndehydrogenase (G6PD), superoxide dismutase (SOD), and\nmalondialdehyde (MDA) in the venous blood of cases were measured\nspectrophotometrically. The values compared with control group,\nthe relation between the severity and distribution of acne, and\nthe correlation of each enzyme level were researched.\nCAT and G6PD levels in patients were found to be\nstatistically decreased, and SOD and MDA levels were found to be\nstatistically increased (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .001). However, any statistical\ndifference and correlation could not be found between the severity\nand distribution of lesions and the mean levels of enzymes. In\naddition, we found that each enzyme is correlated with one another.\nOur findings show that oxidative stress\nexists in the acne patients. It will be useful to apply at least\none antioxidant featured drug along with the combined acne\ntreatment.\n                  <\/jats:p>","DOI":"10.1155\/mi.2005.380","type":"journal-article","created":{"date-parts":[[2005,12,21]],"date-time":"2005-12-21T07:55:05Z","timestamp":1135151705000},"page":"380-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Oxidative Stress in Patients With Acne Vulgaris"],"prefix":"10.1155","volume":"2005","author":[{"given":"Ozer","family":"Arican","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ergul Belge","family":"Kurutas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sezai","family":"Sasmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,14]]},"container-title":["Mediators of Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/mi\/2005\/649082.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/mi\/2005\/649082.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/MI.2005.380","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T06:00:53Z","timestamp":1723096853000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/MI.2005.380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["10.1155\/MI.2005.380"],"URL":"https:\/\/doi.org\/10.1155\/mi.2005.380","archive":["Portico"],"relation":{},"ISSN":["0962-9351","1466-1861"],"issn-type":[{"value":"0962-9351","type":"print"},{"value":"1466-1861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"2005-08-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-09-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-12-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}