{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:50:01Z","timestamp":1787017801627,"version":"build-2736575974"},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":364,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012547","name":"Natural Science Foundation of Guangxi Zhuang Autonomous Region","doi-asserted-by":"publisher","award":["2021GXNSFBA220031"],"award-info":[{"award-number":["2021GXNSFBA220031"]}],"id":[{"id":"10.13039\/100012547","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012547","name":"Natural Science Foundation of Guangxi Zhuang Autonomous Region","doi-asserted-by":"publisher","award":["2024GXNSFAA010265"],"award-info":[{"award-number":["2024GXNSFAA010265"]}],"id":[{"id":"10.13039\/100012547","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neural Plasticity"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    The investigation of brain functional network dynamics offers a promising approach to understanding network reorganization poststroke. This study aims to explore the dynamic network configurations associated with motor recovery in stroke patients and assess their predictive potential using multilayer network analysis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Resting\u2010state functional magnetic resonance imaging data were collected from patients with subacute stroke within 2 weeks of onset and from matched healthy controls (HCs). Group\u2010independent component analysis and a sliding window approach were utilized to construct dynamic functional networks. A multilayer network model was applied to quantify the switching rates of individual nodes, subnetworks, and the global network across the dynamic network. Correlation analyses assessed the relationship between switching rates and motor function recovery, while linear regression models evaluated the predictive potential of global network switching rate on motor recovery outcomes.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Stroke patients exhibited a significant increase in the switching rates of specific brain regions, including the medial frontal gyrus, precentral gyrus, inferior parietal lobule, anterior cingulate, superior frontal gyrus, and postcentral gyrus, compared to HCs. Additionally, elevated switching rates were observed in the frontoparietal network, default mode network, cerebellar network, and in the global network. These increased switching rates were positively correlated with baseline Fugl\u2013Meyer assessment (FMA) scores and changes in FMA scores at 90 days poststroke. Importantly, the global network\u2019s switching rate emerged as a significant predictor of motor recovery in stroke patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    The reorganization of dynamic network configurations in stroke patients reveals crucial insights into the mechanisms of motor recovery. These findings suggest that metrics of dynamic network reorganization, particularly global network switching rate, may offer a robust predictor of motor recovery.\n                  <\/jats:p>","DOI":"10.1155\/np\/9932927","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:09:56Z","timestamp":1735603796000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Reorganization of Dynamic Network in Stroke Patients and Its Potential for Predicting Motor Recovery"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5809-3030","authenticated-orcid":false,"given":"Xiaomin","family":"Pang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longquan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huahang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinfeng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaorong","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianqing","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liren","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9911-6692","authenticated-orcid":false,"given":"Zhao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,30]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000180861.54180.FF"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.1455"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30500-3"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70247-7"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(17)30283-1"},{"key":"e_1_2_12_6_2","first-page":"79","article-title":"The Prognostic Value of Motor-Evoked Potentials in Motor Recovery and Functional Outcome After Stroke\u2212A Systematic Review of the Literature.","volume":"27","author":"Bembenek J. P.","year":"2012","journal-title":"Functional Neurology"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000479594"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.000382"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-011-0972-x"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968316662708"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq043"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2017.09.009"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1590\/1414-431x2022e12036"},{"key":"e_1_2_12_14_2","doi-asserted-by":"crossref","unstructured":"WuK. FangQ. NevilleK. andJelfsB. Evaluation of Module Dynamics in Functional Brain Networks After Stroke 2023 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) 2023 IEEE 1\u20134.","DOI":"10.1109\/EMBC40787.2023.10340633"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-140467"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2016.00084"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.05.079"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.09.036"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2020.102507"},{"key":"e_1_2_12_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcab227"},{"key":"e_1_2_12_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.25366"},{"key":"e_1_2_12_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/gigascience\/gix004"},{"key":"e_1_2_12_23_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1814785115"},{"key":"e_1_2_12_24_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1018985108"},{"key":"e_1_2_12_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1422487112"},{"key":"e_1_2_12_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.05.078"},{"key":"e_1_2_12_27_2","doi-asserted-by":"publisher","DOI":"10.31083\/j.jin2106170"},{"key":"e_1_2_12_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2020.102169"},{"key":"e_1_2_12_29_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2023.1123534"},{"key":"e_1_2_12_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.3316"},{"key":"e_1_2_12_31_2","doi-asserted-by":"publisher","DOI":"10.2340\/1650197771331"},{"key":"e_1_2_12_32_2","article-title":"GRETNA: A Graph Theoretical Network Analysis Toolbox for Imaging Connectomics","volume":"9","author":"Wang J.","year":"2015","journal-title":"Frontiers in Human Neuroscience"},{"key":"e_1_2_12_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.08.048"},{"key":"e_1_2_12_34_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-020-02523-8"},{"key":"e_1_2_12_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs352"},{"key":"e_1_2_12_36_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2011.00002"},{"key":"e_1_2_12_37_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.820641"},{"key":"e_1_2_12_38_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00338.2011"},{"key":"e_1_2_12_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/pcn.13162"},{"key":"e_1_2_12_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.11.006"},{"key":"e_1_2_12_41_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-122414-033634"},{"key":"e_1_2_12_42_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.3129783"},{"key":"e_1_2_12_43_2","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.11.037.2009"},{"key":"e_1_2_12_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2017.12.019"},{"key":"e_1_2_12_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14345"},{"key":"e_1_2_12_46_2","doi-asserted-by":"publisher","DOI":"10.1177\/15459683231177604"},{"key":"e_1_2_12_47_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg245"},{"key":"e_1_2_12_48_2","first-page":"463","article-title":"Motor and Cognitive Impairment After Stroke","volume":"50","author":"Cengic L.","year":"2011","journal-title":"Acta Clinica Croatica"},{"key":"e_1_2_12_49_2","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2002.32739"},{"key":"e_1_2_12_50_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066556"},{"key":"e_1_2_12_51_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2023.1140399"},{"key":"e_1_2_12_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2013.238"},{"key":"e_1_2_12_53_2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.918185"},{"key":"e_1_2_12_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2024.103601"},{"key":"e_1_2_12_55_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24183"},{"key":"e_1_2_12_56_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00548"},{"key":"e_1_2_12_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-022-03950-4"},{"key":"e_1_2_12_58_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41583-019-0212-7"},{"key":"e_1_2_12_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2019.05.022"},{"key":"e_1_2_12_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2017.02.005"},{"key":"e_1_2_12_61_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1044333"},{"key":"e_1_2_12_62_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-021-05187-1"},{"key":"e_1_2_12_63_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-022-01464-7"},{"key":"e_1_2_12_64_2","doi-asserted-by":"publisher","DOI":"10.1177\/1073858414559409"}],"container-title":["Neural Plasticity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/np\/9932927","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:10:04Z","timestamp":1735603804000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/np\/9932927"}},"subtitle":[],"editor":[{"given":"Xiaozheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/np\/9932927"],"URL":"https:\/\/doi.org\/10.1155\/np\/9932927","archive":["Portico"],"relation":{},"ISSN":["2090-5904","1687-5443"],"issn-type":[{"value":"2090-5904","type":"print"},{"value":"1687-5443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2024-07-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9932927"}}