{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:09:13Z","timestamp":1759032553840},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":2556,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":2556,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neural Plasticity"],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:p>Large laboratory animals are the usual\nchoice for complex surgical procedures on the\nspine and spinal cord, such as shortening of the\nspine. It would, however, be advantageous to be\nable to use a small inexpensive mammal like the\nrat. We describe a procedure which allows\nthoracic spondylectomy (T8\u2010T9) to be\nperformed in the rat with a satisfactory survival\nrate (69%). Functional consequences of the\nprocedure on animals with uninjured spinal\ncord were monitored over a period of six\nmonths, at which time histologic examination\nwas performed. There was a good correlation\nbetween operative trauma, consisting of\nmechanical injury to the cord assessed from the\nsurgical notes, and the duration of postoperative\nspinal shock. Animals for which the cord\nappeared laminated or deformed at the time of\nsacrifice tended to show incomplete functional\nrecovery. Cord cavitation developed, in most\nsurviving animals (78%) but did not have a\nmeasurable adverse effect on functional\noutcome. In the present study, the cord was not\nintentionally injured; however, availability of\nthis procedure may facilitate the future\ndevelopment of methods to implement recovery\nof function following spinal cord injury.\n<\/jats:p>","DOI":"10.1155\/np.1993.39","type":"journal-article","created":{"date-parts":[[2007,3,15]],"date-time":"2007-03-15T09:22:50Z","timestamp":1173950570000},"page":"39-52","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Method for Shortening of the Rat Spine and its NeurologicConsequences"],"prefix":"10.1155","volume":"4","author":[{"given":"Luis","family":"de Medinaceli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard Jed","family":"Wyatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1993,1]]},"container-title":["Neural Plasticity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/np\/1993\/946471.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/NP.1993.39","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:55:16Z","timestamp":1723067716000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/NP.1993.39"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1993,1]]}},"alternative-id":["10.1155\/NP.1993.39"],"URL":"https:\/\/doi.org\/10.1155\/np.1993.39","archive":["Portico"],"relation":{},"ISSN":["2090-5904","1687-5443"],"issn-type":[{"type":"print","value":"2090-5904"},{"type":"electronic","value":"1687-5443"}],"subject":[],"published":{"date-parts":[[1993,1]]},"assertion":[{"value":"2000-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}