{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:33:29Z","timestamp":1759530809330},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neural Plasticity"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>Taurine was extracted from <jats:italic>Pegasus later-narius Cuvier<\/jats:italic>\n to study its effects on learning and\nmemory in mice. Mice were treated with different\ndoses of taurine (10 mg\/kg, 20 mg\/kg, 40 mg\/kg).\nThe mice were treated with various chemical\nagents (pentobarbital, cycloheximide, sodium\nnitrite, alcohol) to disrupt the normal memory\nprocess. We measured the effect of taurine on\nstep\u2010down latency (SDL) and escape latency (EL)\nin a passive avoidance task after 10 or 30 days.\nTreatment with taurine alone did not change\neither SDL or EL. Taurine protected mice .from\nthe memory disruption induced by alcohol,\npentobarbital, sodium nitrite, and cycloheximide\nbut had no obvious effect on motor coordination,\nexploratory activity, or locomotor activity as\nmeasured using the rota\u2010rod test and the hole\nboard test. We conclude that taurine can be\neffective in attenuating the amnesia produced\nby alcohol, pentobarbital, cycloheximide, and\nsodium nitrite without compromising the\nbehavioral aspects of the animals tested.<\/jats:p>","DOI":"10.1155\/np.2000.245","type":"journal-article","created":{"date-parts":[[2007,3,15]],"date-time":"2007-03-15T09:22:50Z","timestamp":1173950570000},"page":"245-259","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Improvement of Impaired Memory in Mice by Taurine"],"prefix":"10.1155","volume":"7","author":[{"given":"Bhupinder P. S.","family":"Vohra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Hui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2000,1]]},"container-title":["Neural Plasticity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/np\/2000\/196049.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/np\/2000\/196049.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/NP.2000.245","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T09:00:56Z","timestamp":1723107656000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/NP.2000.245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1155\/NP.2000.245"],"URL":"https:\/\/doi.org\/10.1155\/np.2000.245","archive":["Portico"],"relation":{},"ISSN":["2090-5904","1687-5443"],"issn-type":[{"type":"print","value":"2090-5904"},{"type":"electronic","value":"1687-5443"}],"subject":[],"published":{"date-parts":[[2000,1]]},"assertion":[{"value":"2000-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}