{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T03:15:19Z","timestamp":1776827719067,"version":"3.51.2"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":364,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP19K19591"],"award-info":[{"award-number":["JP19K19591"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing Research and Practice"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p><jats:bold>Aims:<\/jats:bold> To summarize the morphological characteristics and development and healing processes of severe radiodermatitis for examining the factors contributing to the development of severe radiodermatitis in patients with head and neck cancer.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> This scoping review was conducted in accordance with PRISMA extension for Scoping Reviews. Data were extracted from selected references describing detailed conditions of severe radiodermatitis in patients with head and neck cancer. The data were organized separately for radiotherapy, chemoradiotherapy, and bioradiotherapy.<\/jats:p><jats:p><jats:bold>Data Sources:<\/jats:bold> Medline, PubMed, CINAHL, and Cochrane Central Register of Controlled Trials databases were used to search for papers from 2000 to December 2023.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> 11 out of 658 references met the criteria for this review. The morphological characteristics of severe radiodermatitis were categorized by symptoms, site, and shape, and a condition in which moist desquamations and associated crusts spreading to the anterior and lateral neck areas were extracted. In bioradiotherapy, the process of keratinocyte degeneration and formation of blisters under the epidermis leading to moist desquamations was extracted. In chemoradiotherapy, the process of epithelization was extracted 1\u2009week following the occurrence of moist desquamations.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Moist desquamations are more likely to occur in severe radiodermatitis in patients with head and neck cancer. Since they can fuse and spread, preventative measures to mitigate spreading are important. However, there is insufficient information to examine the causes of widespread moist desquamations. For preventing moist desquamations and establishing care methods to heal moist desquamations, it may be necessary to identify the symptoms, site, and shape, including the color tone and depth, and healing process during their occurrence.<\/jats:p>","DOI":"10.1155\/nrp\/1940552","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T04:33:52Z","timestamp":1735619632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Development and Healing Process of Severe Radiodermatitis in Patients With Head and Neck Cancer Undergoing Radiotherapy: A Scoping Review"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9468-2572","authenticated-orcid":false,"given":"Nao","family":"Miyamae","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8799-9026","authenticated-orcid":false,"given":"Yuko","family":"Imakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1909-2262","authenticated-orcid":false,"given":"Mao","family":"Kunimitsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4433-1608","authenticated-orcid":false,"given":"Makoto","family":"Oe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,30]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13371"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-016-0186-4"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-011-1324-4"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2017-0359"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2021.08.009"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000797952.41753.f4"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2354.2002.00287.x"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2022.10.004"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13507"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr139"},{"key":"e_1_2_9_12_2","first-page":"11000","article-title":"Topical Use of Olive Oil Preparation to Prevent Radiodermatitis: Results of a Prospective Study in Nasopharyngeal Carcinoma Patients","volume":"8","author":"Cui Z.","year":"2015","journal-title":"International Journal of Clinical and Experimental Medicine"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-011-1110-3"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11805-008-0058-7"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-022-06829-6"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-012-0385-9"},{"key":"e_1_2_9_17_2","unstructured":"PostM. 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Symptom Management Guidelines: Radiation Dermatitis 2018 https:\/\/www.bccancer.bc.ca\/nursing-site\/Documents\/16.%20Radiation%20Dermatitis.pdf."},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2013.05.005"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES-20-12"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0850"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/jrr\/rrv092"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12317"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijpc.ijpc_32_20"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmrs.397"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/coc.0b013e318193125c"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/1757-1626-2-25"},{"key":"e_1_2_9_27_2","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2008.0454"},{"key":"e_1_2_9_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-008-1829-z"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13210"},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4606-2"},{"key":"e_1_2_9_31_2","unstructured":"WolfJ. 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Radiation Dermatitis\u2013Up to Date 2023 https:\/\/www.uptodate.com\/contents\/radiation-dermatitis."}],"container-title":["Nursing Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/nrp\/1940552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T13:59:43Z","timestamp":1735912783000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/nrp\/1940552"}},"subtitle":[],"editor":[{"given":"Johanna Elizabeth","family":"Maree","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1155\/nrp\/1940552"],"URL":"https:\/\/doi.org\/10.1155\/nrp\/1940552","archive":["Portico"],"relation":{},"ISSN":["2090-1429","2090-1437"],"issn-type":[{"value":"2090-1429","type":"print"},{"value":"2090-1437","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2024-03-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1940552"}}