{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:22:03Z","timestamp":1793643723429,"version":"4.5.1"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":346,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obstetrics and Gynecology International"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    Platelet\u2010rich plasma (PRP) promotes the wound\u2010healing process and reduces pain. Cord blood platelet\u2010rich plasma (CB\u2010PRP), which can be easily collected from the umbilical cord and reapplied to a cesarean section wound, has been proposed to have similar effects as PRP. This paper hypothesizes that CB\u2010PRB would provide beneficial effects in terms of wound healing and pain reduction in women undergoing cesarean section. This study is a randomized controlled trial involving 52 pregnant women who underwent cesarean sections. Participants were assigned to either the intervention group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200926) or the control group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200926) at the Obstetrics and Gynecology Clinic of Police General Hospital. Cord blood PRP was applied to the subcutaneous layer and the surgical wound immediately following the cesarean section. The efficacy of wound healing was evaluated using the REEDA scale score on days 1 and 3 postoperatively, and the Vancouver Scar Scale (VSS) was assessed in the 8th week postoperation. The efficacy in reducing pain was measured using a Visual Analog Scale on days 1 and 3 postoperatively. The mean REEDA scale on day 1 (mean\u2009\u00b1\u2009SD: 1.5\u2009\u00b1\u20090.2561.5\u2009\u00b1\u20090.256 in the CB\u2010PRP group and 2.5\u2009\u00b1\u20090.267 in the control group;\n                    <jats:italic>p<\/jats:italic>\n                    = 0.009) and the mean VSS score at the 8th week (mean\u2009\u00b1\u2009SD: 2.577\u2009\u00b1\u20092.003 in the CB\u2010PRP group and 6.962\u2009\u00b1\u20092.441 in the control group;\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001) were significantly lower in the CB\u2010PRP group than those in the control group. However, there were no differences in Visual Analog Scale values between the two groups. The findings indicate that CB\u2010PRP potentially promotes wound healing following cesarean sections but does not reduce pain. Further research is needed to confirm the beneficial effects of CB\u2010PRP.\n                  <\/jats:p>","DOI":"10.1155\/ogi\/4155779","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T07:35:42Z","timestamp":1733988942000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cord Blood Platelet\u2010Rich Plasma in Cesarean Section Wound Management"],"prefix":"10.1155","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3711-4905","authenticated-orcid":false,"given":"Amornrat","family":"Thanachaiviwat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1649-5744","authenticated-orcid":false,"given":"Sutham","family":"Suthaporn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8512-1658","authenticated-orcid":false,"given":"Patana","family":"Teng-umnuay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2020.29.sup11a.s1"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475x.2008.00410.x"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.26"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/09537104.2020.1849605"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.4103\/jomfp.jomfp_93_18"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12690"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-018-0860-1"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/adj.12754"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13714"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19095284"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.240450403"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2019.102716"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.34449"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/504723"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.04.007"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.30886"},{"key":"e_1_2_11_17_2","doi-asserted-by":"crossref","DOI":"10.1053\/j.semvascsurg.2017.12.001","volume-title":"Efficacy of Cord Blood Platelet Gel Application for Enhancing Diabetic Foot Ulcer Healing After Lower Limb Revascularization","author":"Volpe P.","year":"2017"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j2835"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0091-2182(90)90166-3"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-200021030-00005"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2015.02.043"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.55374\/jseamed.v3i1.43"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01203.x"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.7150\/thno.21234"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2021.155756"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.18295\/squmj.2016.16.01.002"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12015-013-9494-8"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2016.08.063"},{"key":"e_1_2_11_29_2","article-title":"Use of Platelet Rich Plasma Gel on Wound Healing: A Systematic Review and Meta-Analysis","volume":"11","author":"Carter M. 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