{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:09:41Z","timestamp":1779361781854,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":140,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006920","name":"University of Pennsylvania","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007226","name":"Villanova University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obstetrics and Gynecology International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective was to compare the performance of three postpartum hemorrhage risk screening tools with a known patient data set.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>This is a retrospective secondary data analysis of a parent study whose aim was to develop a novel biomarker for detecting elevated blood loss with childbirth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>A single tertiary care hospital in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Inclusion criteria for the parent study were \u2265 37\u2009weeks, \u2265 18\u2009years, and pregnancy with one live fetus (no multiples). Eligible participants were identified upon admission to the labor unit and enrolled after informed consent was obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods\/Main Outcome Measures<\/jats:title>\n                    <jats:p>\n                      Statistical analyses were computed using Stata SE, v18. Bivariate associations between binary outcomes and continuous measures were calculated using independent\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests. Bivariate associations between binary outcomes and categorical measures were calculated using chi\u2010square tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Recruitment occurred June through September 2021 and included\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009525 participants. When using the American College of Obstetricians and Gynecologists\u2019 threshold of \u2265 1000\u2009mL, 13.3% (n\u2009=\u200970) of parturients experienced a hemorrhage. When using the World Health Organization\u2019s definition of postpartum hemorrhage of \u2265 500\u2009mL, the prevalence of hemorrhage was 36.8% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009193). Sensitivity was highest in identifying hemorrhage with the Association of Women\u2019s Health, Obstetric and Neonatal Nurses\u2019 tool. When high\u2010 and medium\u2010risk scores were considered, the tool had 86% (95% CI: 83.0%\u201389.0%) accuracy in identifying cases of hemorrhage. This tool also had the highest negative predictive value (78.7%, CI 75.2%\u201382.2%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The tool with the highest sensitivity and negative predictive values identified 21% of cases as \u201clow risk\u201d that went on to experience blood loss \u2265 500\u2009mL, thus underscoring the need for better predictive models.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/ogi\/9576600","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:04:27Z","timestamp":1779361467000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Direct Comparison of Three Postpartum Hemorrhage Risk Assessment Tools: A Retrospective Secondary Data Analysis"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3282-3925","authenticated-orcid":false,"given":"Stefanie","family":"Modri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9393-3544","authenticated-orcid":false,"given":"Mohika","family":"Nagpal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1948-992X","authenticated-orcid":false,"given":"Margaret","family":"Brace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3762-5508","authenticated-orcid":false,"given":"Yvonne Nicole","family":"Reddick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8167-9163","authenticated-orcid":false,"given":"James","family":"Weimer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7706-5035","authenticated-orcid":false,"given":"Harish","family":"Sehdev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2462-5561","authenticated-orcid":false,"given":"Kimberly Kovach","family":"Trout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,5,21]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(24)00560-6"},{"key":"e_1_2_11_2_2","volume-title":"CDC Newsroom","author":"Centers for Disease Control & Prevention","year":"2022"},{"key":"e_1_2_11_3_2","unstructured":"Who A Roadmap to Combat Postpartum Hemorrhagehemorrhage Between 2023 and 2030 2023 https:\/\/who.int\/publications\/i\/item\/9789240081802."},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/FM9.0000000000000261"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2303966"},{"key":"e_1_2_11_6_2","unstructured":"California Maternal Quality Care Collaborative OB Hemorrhage Toolkit v3.0 7.18 2022 https:\/\/www.cmqcc.org\/resources-tool-kits\/toolkits\/ob-hemorrhagehemorrhage-toolkit."},{"key":"e_1_2_11_7_2","first-page":"e168","article-title":"Postpartum Hemorrhage","volume":"130","author":"American College of Obstetricians and Gynecologists","year":"2017","journal-title":"American College of Obstetricians and Gynecologists"},{"key":"e_1_2_11_8_2","unstructured":"American College of Obstetricians and Gynecologists Safe Motherhood Initiative: Obstetric Hemorrhage 2024 https:\/\/www.acog.org\/community\/districts-and-sections\/district-ii\/programs-and-resources\/safe-motherhood-initiative\/obstetric-hemorrhage."},{"key":"e_1_2_11_9_2","unstructured":"Association of Women\u2019s HealthandObstetric and Neonatal Nurses Postpartum Hemorrhage Project 2017."},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1710501"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2022.08.003"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004579"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1712166"},{"key":"e_1_2_11_14_2","doi-asserted-by":"crossref","unstructured":"TroutK. 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VIBRANT: Early Prediction of life-threatening Uterine Atony Using Maternal Heart Rate Proceedings of the IEEE\/ACM Conference: Connected Health Applications Systems & Engineering Technologies June 2025.","DOI":"10.1145\/3721201.3721379"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_11_16_2","volume-title":"WHO Recommendations for the Prevention and Treatment of Postpartum Hemorrhagehemorrhage","author":"World Health Organization","year":"2012"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1975-4688"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-021-06377-"}],"container-title":["Obstetrics and Gynecology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/ogi\/9576600","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/ogi\/9576600","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/ogi\/9576600","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:04:30Z","timestamp":1779361470000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/ogi\/9576600"}},"subtitle":[],"editor":[{"given":"Hannah","family":"Wesley","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/ogi\/9576600"],"URL":"https:\/\/doi.org\/10.1155\/ogi\/9576600","archive":["Portico"],"relation":{},"ISSN":["1687-9589","1687-9597"],"issn-type":[{"value":"1687-9589","type":"print"},{"value":"1687-9597","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9576600"}}