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The upregulated shared gene set between HSV\u20101 infection and PD is mainly enriched in neuroinflammation, while the downregulated shared gene set is mainly enriched in stem cell and cellular metabolism, and the drug repurposing targeted the shared molecular signature nalfurafine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HSV\u20101 infection is related to PD, and these two diseases had shared molecular signature such as neuroinflammation and stem cell, which could be targeted for drug repurposing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/padi\/4044371","type":"journal-article","created":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T10:02:21Z","timestamp":1766484141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genome\u2010Wide Association Studies Data and 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