{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:52:04Z","timestamp":1773010324777,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":64,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Diabetes"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Type 1 diabetes (T1D) incidence is rising globally, with significant regional variation. Data from highly homogeneous populations, such as Lithuanian, may contribute to a better understanding of contributing T1D factors. This study examines 24\u2010year trends in childhood T1D incidence and seasonal patterns in Lithuania.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The annual incidence rates (IRs) were computed utilizing established methodologies per 100,000 children &lt;15 years. The study included 2369 (1181 boys) patients with T1D.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During 2001\u20132024, the mean IR was 21.4 per 100,000\u2009&lt;\u200915 years (95% CI: 20.89, 27.28). The incidence rose from 10.8 to 36.4 per 100,000 children under 15 years of age, with notable peaks observed in 2021 and 2022, temporally aligning with the highest COVID\u201019 infection waves. Subgroup analysis showed the most rapid increase in young teenagers (10\u201314 years). Most new cases (63.5%) were diagnosed from September to March.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study demonstrates a rapidly increasing incidence of T1D in Lithuanian children over a 24\u2010year period and is one of the highest in European countries. The seasonal distribution of new cases has been speculated to be due to reduced sunlight exposure and lower vitamin D levels, as well as increased school related stress and viral infections during autumn and winter months. However, additional contributing factors are likely involved, underscoring the need for further research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/pedi\/9968982","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:10:39Z","timestamp":1773004239000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiological Trends and Seasonal Patterns in Childhood Type 1 Diabetes: Insights From 2001 to 2024 in Lithuania"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0228-7143","authenticated-orcid":false,"given":"Ingrida","family":"Stankute","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale","family":"Marciulionyte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rytas","family":"Ostrauskas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aiste","family":"Cemerkaite","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gryte","family":"Leonaviciute","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robertas","family":"Kemezys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigita","family":"Vainiene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kastytis","family":"Smigelskas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rasa","family":"Verkauskiene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2025.112277"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00276-5"},{"key":"e_1_2_12_3_2","unstructured":"World 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