{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T08:43:11Z","timestamp":1776242591832,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"vor","delay-in-days":104,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulmonary Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Identifying graft rejection after lung transplantation remains challenging, and no consensus exists on the optimal surveillance strategy. Transbronchial forceps biopsy (FBx) is the conventional method but is limited by small sample size and crush artifacts. Sheath\u2010guided cryobiopsy (CBx) using a novel 1.1\u2010mm probe has emerged as a promising alternative. This study evaluates the feasibility and safety of the 1.1\u2010mm cryoprobe and provides a focused review of current literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective observational single\u2010center study between October 2022 and January 2023 of adult lung transplant recipients who underwent transbronchial biopsies for surveillance. Procedures were performed using either standard FBx or the 1.1\u2010mm cryoprobe. Descriptive analyses compared feasibility and safety between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 72 lung transplant recipients who underwent 109 surveillance biopsies. A total of\n                      <jats:italic>n<\/jats:italic>\n                      = 56\u2009CBx and\n                      <jats:italic>n<\/jats:italic>\n                      = 53\u2009FBx procedures were performed. The median procedure time was 20\u2009min (IQR 17\u201326) in the CBx group versus 22\u2009min (IQR 15\u201333) in the FBx group. We found a statistically higher median sample area for CBx compared with FBx (11 vs. 6\u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      ,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.01). No pneumothorax or postprocedural respiratory failure occurred in either group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CBx with a 1.1\u2010mm probe provides larger histological samples than FBx, with comparable safety and potentially shorter procedural times. These findings support its feasibility for lung transplant surveillance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/pm\/3558336","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T07:46:38Z","timestamp":1776239198000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and Safety of 1.1\u2010mm Cryobiopsy for Acute Rejection Surveillance in Lung Transplant Recipients: A Comparative Study and Review of the Literature"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8332-8682","authenticated-orcid":false,"given":"Alanna","family":"Barrios-Ruiz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1384-6761","authenticated-orcid":false,"given":"Alejandra","family":"Yu 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