{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T10:03:21Z","timestamp":1790157801596,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":265,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["RS-2024-00449485"],"award-info":[{"award-number":["RS-2024-00449485"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003718","name":"Korea Institute of Oriental Medicine","doi-asserted-by":"publisher","award":["KSN2511011"],"award-info":[{"award-number":["KSN2511011"]}],"id":[{"id":"10.13039\/501100003718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Acupuncture involves selecting acupoints distributed across the body, yet the spatial organization of this process remains unclear. Previous studies have identified frequently used acupoints across conditions but have paid limited attention to their spatial organization. Here, we analyzed patterns of acupoint selection across seven pain conditions, including episodic migraine, low back pain, dysmenorrhea, irritable bowel syndrome, carpal tunnel syndrome, osteoarthritis, and ankle sprain, using a dataset derived from randomized controlled trials. Acupoints were classified into six anatomical regions, and regional usage patterns were quantified and visualized. Acupoint selection showed two recurrent tendencies. Acupoints near the disease site were preferentially selected, reflecting region\u2010specific recruitment. In contrast, distal extremity points were repeatedly used across conditions, with the lower\u2010limb tendency being most evident in head\/trunk conditions, reflecting cross\u2010regional recruitment. Across the seven included conditions, distal extremity regions emerged as recurrent cross\u2010regional components of acupoint selection. This region\u2010level perspective complements point\u2010frequency analyses by showing how acupoint selection is organized across the body.<\/jats:p>","DOI":"10.1155\/prm\/2707225","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T09:14:50Z","timestamp":1790154890000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spatial Organization of Acupoint Selection Across Pain Conditions"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6770-4166","authenticated-orcid":false,"given":"Heeyoung","family":"Moon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6718-273X","authenticated-orcid":false,"given":"Da-Eun","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9275-3111","authenticated-orcid":false,"given":"In-Seon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6787-2215","authenticated-orcid":false,"given":"Younbyoung","family":"Chae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12761"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2018.29047.vtn"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.671"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joim.2024.12.004"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185x.70226"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2026.1704570"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.1049887"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1155\/prm\/5799642"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10102059"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.894951"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/0964528420926173"},{"key":"e_1_2_13_12_2","first-page":"1591","article-title":"Acupoints Compatibility Rules of Acupuncture for Functional Gastrointestinal Disorders Based on Data Mining Technology: A Systematic Review","volume":"54","author":"Li H.","year":"2025","journal-title":"Iranian Journal of Public Health"},{"key":"e_1_2_13_13_2","doi-asserted-by":"publisher","DOI":"10.2147\/jpr.s471441"},{"key":"e_1_2_13_14_2","doi-asserted-by":"publisher","DOI":"10.2147\/jpr.s624742"},{"key":"e_1_2_13_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/0964528420971309"},{"key":"e_1_2_13_16_2","first-page":"115","article-title":"Observation on the Clinical Effect of Acupuncture on Abducens Nerve Palsy Guided by Biaoben Genjie Theory","volume":"51","author":"Guan X. R.","year":"2026","journal-title":"Zhen Ci Yan Jiu"},{"key":"e_1_2_13_17_2","doi-asserted-by":"publisher","DOI":"10.13702\/j.1000-0607.20221382"},{"key":"e_1_2_13_18_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/4827123"},{"key":"e_1_2_13_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnint.2019.00038"},{"key":"e_1_2_13_20_2","first-page":"456","article-title":"Acupoints Selection Based on Disease-Symptom-Location Combination and Acupuncture Treatment of Pattern\/Syndrome Differentiation","volume":"36","author":"Zhang X.","year":"2016","journal-title":"Zhongguo Zhen Jiu"}],"container-title":["Pain Research and Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/prm\/2707225","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/prm\/2707225","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/prm\/2707225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T09:14:54Z","timestamp":1790154894000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/prm\/2707225"}},"subtitle":[],"editor":[{"given":"Suraiya","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/prm\/2707225"],"URL":"https:\/\/doi.org\/10.1155\/prm\/2707225","archive":["Portico"],"relation":{},"ISSN":["1203-6765","1918-1523"],"issn-type":[{"value":"1203-6765","type":"print"},{"value":"1918-1523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-05-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2707225"}}