{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T14:50:43Z","timestamp":1772981443224,"version":"3.50.1"},"reference-count":103,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":241,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Pectus excavatum is a common congenital chest wall deformity that can lead to significant cardiopulmonary compression and psychological distress. The minimally invasive Nuss procedure is the standard treatment, but it often results in severe postoperative pain. Effective perioperative pain management is essential to enhance recovery and improve patient outcomes.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    This study aimed to synthesize the most effective evidence on perioperative pain management in patients with pectus excavatum and to provide evidence\u2010based management methods for clinical teams and patients undergoing this surgery.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Guided by the \u201c6S\u201d pyramid model, we retrieved evidence on perioperative pain management from relevant websites, databases, and unpublished gray literature. The search timeframe ranged from 2014 to December 2024. Two researchers independently evaluated the literature quality using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) for guidelines and the Joanna Briggs Institute (JBI) critical appraisal tool for other types of literature. Two researchers independently extracted and summarized the evidence according to the principle of high\u2010quality evidence and newly published evidence.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    A total of 39 articles were retrieved, of which 6 were guidelines, 6 were expert consensus, 7 were systematic reviews, 1 was a clinical decision, 11 were randomized controlled trials, and 8 were cohort studies. Overall, 35 pieces of evidence from seven dimensions\u2014general principles, education and counseling, pain assessment, preemptive analgesia, intraoperative analgesia, postoperative pain management, and pain management after discharge\u2014were summarized.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    This study summarized the best evidence on perioperative pain management in patients with pectus excavatum, providing a comprehensive and scientific approach to enhance recovery and patient satisfaction.\n                  <\/jats:p>","DOI":"10.1155\/prm\/8823617","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T08:50:25Z","timestamp":1756543825000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Best Evidence Summary for Perioperative Pain Management in Patients With Pectus Excavatum"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3292-4617","authenticated-orcid":false,"given":"Yi","family":"Liang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6423-3581","authenticated-orcid":false,"given":"Huajian","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3259-028X","authenticated-orcid":false,"given":"Xinxin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6606-3201","authenticated-orcid":false,"given":"Guanbiao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,30]]},"reference":[{"key":"e_1_2_14_1_2","first-page":"7","article-title":"Chinese Expert Consensus on Funnel Thoracic Surgery Treatment","volume":"1","author":"The Thoracic and Cardiovascular Surgery Group of the Pediatric Surgery Branch of the Chinese Medical Association and the Thoracic Surgery Branch of the Guangdong Medical Doctor Association","year":"2020","journal-title":"Chinese Journal of Pediatric Surgery"},{"key":"e_1_2_14_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232575"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-21-1671"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32834881c4"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2020.12.068"},{"key":"e_1_2_14_6_2","volume-title":"Overview of Postoperative Analgesia in Children and Progress of Postoperative Analgesia After Nuss Surgery in Children Funnel Chest","author":"Feng X.","year":"2017"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2018.05.010"},{"key":"e_1_2_14_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13942"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13030844"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.3785\/j.issn.1008-9292.2013.02.016"},{"key":"e_1_2_14_11_2","first-page":"2669","article-title":"Research Progress in Postoperative Pain Management","volume":"32","author":"Su M.","year":"2018","journal-title":"Nursing Research"},{"key":"e_1_2_14_12_2","first-page":"504","article-title":"Research Progress of Analgesia After Nuss Surgery","volume":"24","author":"Zhang G.","year":"2024","journal-title":"Chinese Journal of Minimally Invasive Surgery"},{"key":"e_1_2_14_13_2","first-page":"364","article-title":"Application of Different Analgesic Methods in Children After Nuss Surgery","volume":"38","author":"Feng X. Y.","year":"2017","journal-title":"International Journal of Anesthesiology and Resuscitation"},{"key":"e_1_2_14_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40122-022-00439-0"},{"key":"e_1_2_14_15_2","first-page":"751","article-title":"Application of Multimode Analgesia Based Predominantly Upon Single Thoracic Epidural Block During Pediatric Nuss Procedure","volume":"22","author":"Fuzhou Z.","year":"2023","journal-title":"Journal of Clinical Pediatric Surgery"},{"key":"e_1_2_14_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2021.12.049"},{"key":"e_1_2_14_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2022.01.051"},{"key":"e_1_2_14_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2024.07.019"},{"key":"e_1_2_14_19_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-2249-7588"},{"key":"e_1_2_14_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-024-05838-2"},{"key":"e_1_2_14_21_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2019.03.063"},{"key":"e_1_2_14_22_2","doi-asserted-by":"publisher","DOI":"10.5090\/jcs.23.139"},{"key":"e_1_2_14_23_2","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2023.1305326"},{"key":"e_1_2_14_24_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-023-02197-8"},{"key":"e_1_2_14_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezy301"},{"key":"e_1_2_14_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0000000000001328"},{"key":"e_1_2_14_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sempedsurg.2024.151459"},{"key":"e_1_2_14_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000449"},{"key":"e_1_2_14_29_2","doi-asserted-by":"publisher","DOI":"10.1177\/10892532241235750"},{"key":"e_1_2_14_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2024.151727"},{"key":"e_1_2_14_31_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.090449"},{"key":"e_1_2_14_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000055"},{"key":"e_1_2_14_33_2","doi-asserted-by":"publisher","DOI":"10.11124\/JBIES-22-00430"},{"key":"e_1_2_14_34_2","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES-20-05"},{"key":"e_1_2_14_35_2","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES-24-01"},{"key":"e_1_2_14_36_2","unstructured":"The Joanna Briggs Institute Levels of Evidence and Grades of Recommendation Working Party JBI Grades of Recommendation 2014 https:\/\/jbi.global\/sites\/default\/files\/2019-05\/JBI-grades-of-recommendation_2014.pdf."},{"key":"e_1_2_14_37_2","unstructured":"The Joanna Briggs Institute Levels of Evidence and Grades of Recommendation Working Party JBI Levels of Evidence 2014 https:\/\/jbi.global\/sites\/default\/files\/2019-05\/JBI-Levels-of-evidence_2014_0.pdf."},{"key":"e_1_2_14_38_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezae166"},{"key":"e_1_2_14_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.accpm.2024.101427"},{"key":"e_1_2_14_40_2","volume-title":"Guidelines for the Provision of Anaesthetic Services","author":"Royal College of Anaesthetists","year":"2024"},{"key":"e_1_2_14_41_2","first-page":"1159","article-title":"Clinical Practice Guide for Acupoint Stimulation Assisted Treatment of Postoperative Pain","volume":"41","author":"Anesthesia Committee of Chinese Society of Integrated Traditional and Western Medicine","year":"2021","journal-title":"Chinese Journal of Anesthesiology"},{"key":"e_1_2_14_42_2","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13639"},{"key":"e_1_2_14_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2015.12.008"},{"key":"e_1_2_14_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/anae.16391"},{"key":"e_1_2_14_45_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000006441"},{"key":"e_1_2_14_46_2","first-page":"119","article-title":"Chinese Expert Consensus on Perioperative Goal-Oriented Whole-Process Analgesia Management","volume":"17","author":"Zhang X. G.","year":"2021","journal-title":"Chinese Journal of Pain Science"},{"key":"e_1_2_14_47_2","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112137-20201108-03034"},{"key":"e_1_2_14_48_2","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn101379-20190915-00075"},{"key":"e_1_2_14_49_2","doi-asserted-by":"publisher","DOI":"10.7507\/1007-4848.201810052"},{"key":"e_1_2_14_50_2","doi-asserted-by":"publisher","DOI":"10.3390\/jpm14040411"},{"key":"e_1_2_14_51_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-023-02221-x"},{"key":"e_1_2_14_52_2","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2023.1235120"},{"key":"e_1_2_14_53_2","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15609"},{"key":"e_1_2_14_54_2","doi-asserted-by":"publisher","DOI":"10.4097\/kja.21133"},{"key":"e_1_2_14_55_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivaa151"},{"key":"e_1_2_14_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2020.01.023"},{"key":"e_1_2_14_57_2","unstructured":"UpToDate Pectus Excavatum: Treatment 2024 https:\/\/www.uptodate.com\/contents\/pectus-excavatum-treatment."},{"key":"e_1_2_14_58_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13237264"},{"key":"e_1_2_14_59_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-2117-4628"},{"key":"e_1_2_14_60_2","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2024.27.425"},{"key":"e_1_2_14_61_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-024-03354-0"},{"key":"e_1_2_14_62_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11164695"},{"key":"e_1_2_14_63_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/5776833"},{"key":"e_1_2_14_64_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1697911"},{"key":"e_1_2_14_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2019.02.057"},{"key":"e_1_2_14_66_2","doi-asserted-by":"publisher","DOI":"10.1097\/ajp.0000000000000449"},{"key":"e_1_2_14_67_2","doi-asserted-by":"publisher","DOI":"10.1097\/aap.0000000000000071"},{"key":"e_1_2_14_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2024.07.003"},{"key":"e_1_2_14_69_2","doi-asserted-by":"publisher","DOI":"10.1097\/sla.0000000000006113"},{"key":"e_1_2_14_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2023.01.059"},{"key":"e_1_2_14_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2022.10.051"},{"key":"e_1_2_14_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2023.02.036"},{"key":"e_1_2_14_73_2","doi-asserted-by":"publisher","DOI":"10.1097\/sla.0000000000005440"},{"key":"e_1_2_14_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2023.01.028"},{"key":"e_1_2_14_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2021.10.034"},{"key":"e_1_2_14_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nec.2022.02.002"},{"key":"e_1_2_14_77_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.2240"},{"key":"e_1_2_14_78_2","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S142147"},{"key":"e_1_2_14_79_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0304968"},{"key":"e_1_2_14_80_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2023-001665"},{"key":"e_1_2_14_81_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09464-8"},{"key":"e_1_2_14_82_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-024-03608-5"},{"key":"e_1_2_14_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2021.11.032"},{"key":"e_1_2_14_84_2","doi-asserted-by":"publisher","DOI":"10.3390\/children6120132"},{"key":"e_1_2_14_85_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2020.03.007"},{"key":"e_1_2_14_86_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-024-03539-w"},{"key":"e_1_2_14_87_2","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000305"},{"key":"e_1_2_14_88_2","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v12.i4.681"},{"key":"e_1_2_14_89_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40122-022-00367-z"},{"key":"e_1_2_14_90_2","article-title":"From Acute to Chronic Postsurgical Pain: The Significance of the Acute Pain Response","volume":"65","author":"Blichfeldt-Eckhardt M. R.","year":"2018","journal-title":"Danish Medical Journal"},{"key":"e_1_2_14_91_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e24387"},{"key":"e_1_2_14_92_2","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2018.1462785"},{"key":"e_1_2_14_93_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-023-05429-7"},{"key":"e_1_2_14_94_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004987"},{"key":"e_1_2_14_95_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40122-024-00688-1"},{"key":"e_1_2_14_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2017.10.026"},{"key":"e_1_2_14_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2013.07.007"},{"key":"e_1_2_14_98_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjpain.2015.12.010"},{"key":"e_1_2_14_99_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1553-7250(08)34065-3"},{"key":"e_1_2_14_100_2","doi-asserted-by":"publisher","DOI":"10.1097\/pq9.0000000000000688"},{"key":"e_1_2_14_101_2","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2012.25.4.267"},{"key":"e_1_2_14_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2023.04.044"},{"key":"e_1_2_14_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2020.07.558"}],"container-title":["Pain Research and Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/prm\/8823617","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/prm\/8823617","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/prm\/8823617","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:20:07Z","timestamp":1772958007000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/prm\/8823617"}},"subtitle":[],"editor":[{"given":"Massimiliano","family":"Valeriani","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":103,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/prm\/8823617"],"URL":"https:\/\/doi.org\/10.1155\/prm\/8823617","archive":["Portico"],"relation":{},"ISSN":["1203-6765","1918-1523"],"issn-type":[{"value":"1203-6765","type":"print"},{"value":"1918-1523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8823617"}}