{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T07:03:54Z","timestamp":1788246234986,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":53,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Office hysteroscopy (OH) is the standard diagnostic method for evaluating intrauterine and endocervical pathology, yet the fear of procedural pain remains a major barrier to patient acceptance. This study examined whether menstrual pain can be used as a clinical reference to anticipate OH procedural pain and explored other predictors of procedural discomfort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A historical cohort study was conducted among women undergoing OH for abnormal uterine bleeding or postmenopausal bleeding at a tertiary referral hospital between 2014 and 2024. All procedures were performed by a single experienced hysteroscopist using a 4.9\u2010mm vaginoscopic technique with preprocedural acetaminophen. Menstrual pain and OH procedural pain were assessed using a 0\u201310 visual analogue scale (VAS). Demographic and clinical variables were extracted from medical records. Associations with OH pain were evaluated using Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      tests and multivariable linear regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 488 women were included (median age: 45\u2009years and median BMI: 24.5\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). Median VAS for menstrual pain was 1.0 (interquartile range [IQR]: 0\u20133) and for OH pain was 0.0 (IQR: 0\u20132). Mean OH pain was lower than mean menstrual pain. In bivariate analyses, younger age, nulliparity, and higher menstrual pain were associated with higher OH pain. In multivariable analysis, menstrual pain and nulliparity remained independent predictors of higher OH procedural pain, while increasing age was associated with slightly lower pain.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OH was generally well tolerated, with pain typically lower than menstrual pain. Although menstrual pain, parity, and age explained only a modest proportion of pain variability, menstrual pain history offers a simple and patient\u2010centered way to help clinicians set realistic expectations about procedural discomfort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/prm\/8879788","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:35:46Z","timestamp":1772966146000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association Between Menstrual Pain and Procedural Pain During Office Hysteroscopy: A 10\u2010Year Cohort Study"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8876-3138","authenticated-orcid":false,"given":"Tricia Dewi","family":"Anggraeni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7079-7794","authenticated-orcid":false,"given":"Gerald Sebastian","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9091-3716","authenticated-orcid":false,"given":"Fitriyadi","family":"Kusuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5019-2707","authenticated-orcid":false,"given":"Gatot","family":"Purwoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,23]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13669-024-00377-y"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/women5030032"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/jog.15219"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/jog.15738"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-020-05885-9"},{"key":"e_1_2_12_6_2","article-title":"The Influence of Pain Expectation on Pain Experience After Orthopedic Surgery: An Observational Cohort Study","volume":"86","author":"Ng K. L. V.","year":"2020","journal-title":"Minerva Anestesiologica"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2023.04.005"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14103427"},{"key":"e_1_2_12_9_2","first-page":"12","article-title":"Clinical Association of Body Symptoms and Primary Dysmenorrhea Among Young and Middle-Aged Women: An Observational Study","author":"Tseng T.-G.","year":"2025","journal-title":"Frontiers of Medicine"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.4082\/kjfm.21.0103"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare13161954"},{"key":"e_1_2_12_12_2","doi-asserted-by":"crossref","unstructured":"NaiaZ. Pati\u00f1o N\u00fa\u00f1ezS. andBelloO. Visceral Pain and Sensitisation in Women With Dysmenorrhea: A Narrative Review 2024.","DOI":"10.5114\/pq\/172013"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpain.2024.1365193"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.20272"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.24234"},{"key":"e_1_2_12_16_2","first-page":"63","article-title":"Dysmenorrhea is Associated With a Higher Incidence of Pain After Diagnostic Hysteroscopy or Treatment","volume":"17","author":"Pan Y.-Y.","year":"2021","journal-title":"Signa Vitae"},{"key":"e_1_2_12_17_2","article-title":"Dysmenorrhea is Associated With a Higher Incidence of Pain After Diagnostic Hysteroscopy or Treatment: A Commentary","volume":"17","author":"Varrassi G.","year":"2021","journal-title":"Signa Vitae"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-1764361"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2023.07.009"},{"key":"e_1_2_12_20_2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58081132"},{"key":"e_1_2_12_21_2","doi-asserted-by":"publisher","DOI":"10.5055\/jom.2021.0680"},{"key":"e_1_2_12_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-024-11916-x"},{"key":"e_1_2_12_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2021.01.028"},{"key":"e_1_2_12_24_2","article-title":"Should It Hurt?\u2014Experiences of Out-Patient Clinic-Based Hysteroscopy","author":"Nunnerley J.","year":"2025","journal-title":"The Australian and New Zealand Journal of Obstetrics and Gynaecology"},{"key":"e_1_2_12_25_2","unstructured":"HooverK.andRileyK. Pain Management for In-Office Uterine and Cervical Procedures 2025."}],"container-title":["Pain Research and Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/prm\/8879788","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/prm\/8879788","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/prm\/8879788","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:35:48Z","timestamp":1772966148000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/prm\/8879788"}},"subtitle":[],"editor":[{"given":"Massimiliano","family":"Valeriani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/prm\/8879788"],"URL":"https:\/\/doi.org\/10.1155\/prm\/8879788","archive":["Portico"],"relation":{},"ISSN":["1203-6765","1918-1523"],"issn-type":[{"value":"1203-6765","type":"print"},{"value":"1918-1523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-04-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"8879788"}}