{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:35:38Z","timestamp":1789871738291,"version":"4.0.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"vor","delay-in-days":302,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare and evaluate the effect of ProTaper Ultimate root canal instrumentation on postoperative pain level of mandibular first molars showing symptomatic irreversible pulpitis and symptomatic apical periodontitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>\n                      Forty patients referred to root canal treatment of the mandibular first molar were randomly divided into two equal groups according to the rotary file system used in the chemomechanical preparation: ProTaper Ultimate (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920) and ProTaper Gold (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920). After evaluating the preoperative pain score using the visual analog scale, the root canal treatment was performed in a single visit using a standardized protocol by a single operator. Postoperatively, the pain scores were recorded at 24\u2010, 72\u2010h, and 7\u2010day intervals. Statistical analysis was performed at a significance of 0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No significant difference was shown between the ProTaper Ultimate and the ProTaper Gold groups in the intensity of postoperative pain at all time intervals. The postoperative pain score was zero at 7\u2009days postoperatively for both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The ProTaper Ultimate files\u2019 effect on postoperative pain is equivalent to that of the ProTaper Gold files.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>The ProTaper Ultimate files\u2019 effect on postoperative pain is equivalent to that of the ProTaper Gold files. ProTaper Ultimate and ProTaper Gold rotary file systems can be equally and safely used in single\u2010visit root canal treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>ClinicalTrials.gov identifier: NCT05747183<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/prm\/9718875","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:17:49Z","timestamp":1761823069000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effect of ProTaper Ultimate and ProTaper Gold on Postoperative Pain in Mandibular First Molars With Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis: A Randomized Control Clinical Trial"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7656-1136","authenticated-orcid":false,"given":"M.","family":"Hajwel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3220-0563","authenticated-orcid":false,"given":"R.","family":"Elemam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9266-7838","authenticated-orcid":false,"given":"T.","family":"Elsewify","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4822-5503","authenticated-orcid":false,"given":"B.","family":"Eid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,30]]},"reference":[{"key":"e_1_2_12_1_2","volume-title":"Cohen\u2019s Pathways of the Pulp","author":"Berman L.","year":"2021"},{"key":"e_1_2_12_2_2","first-page":"13","article-title":"Endodontic Postoperative Pain: Etiology and Related Factors-An Update","volume":"5","author":"Alamassi B. 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