{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T15:10:33Z","timestamp":1785510633254,"version":"3.56.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":211,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100018556","name":"Science and Technology Program of Suzhou","doi-asserted-by":"publisher","award":["WZYW2022014"],"award-info":[{"award-number":["WZYW2022014"]}],"id":[{"id":"10.13039\/501100018556","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018916","name":"Suzhou Municipal Health Commission","doi-asserted-by":"publisher","award":["202312"],"award-info":[{"award-number":["202312"]}],"id":[{"id":"10.13039\/100018916","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Radiology Research and Practice"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the safety and efficacy of an improved sealed venous indwelling needle for ultrasound\u2010guided sclerotherapy of thyroid cysts in comparison with the standard percutaneous transhepatic cholangiography (PTC) needles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two trapezoidal incisions (2\u2009mm in topline, 1\u2009mm in baseline, and 1\u2009mm in height) were made along the needle core groove at the soft distal end of a sealed venous indwelling needle to create a novel open\u2010window sealed venous indwelling needle. To evaluate the efficacy and safety of this improved needle, we conducted a prospective cohort study with a historical control group, comparing the improved needle with standard 21\u2010gauge PTC needles in the treatment of 68 cystic thyroid nodules. Key outcomes included technical success, which encompasses successful needle placement, complete aspiration, and sclerosant delivery, as well as a reduction in cyst volume at the 3\u2010month follow\u2010up, and procedural outcomes, complications (bleeding, infection, and extravasation), procedural pain, and patient satisfaction (assessed using a 5\u2010point Likert scale).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty\u2010eight cysts in 52 patients (median age, 54\u2009years) were treated. Technical success was achieved in 94.1% (32\/34) procedures versus 87.5% (28\/34) in the PTC needle cohort (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.27). The mean cyst volume reduction was 82.51% (range, 52%\u2013100%) at 3\u2009months. Complications occurred in 3 (two hematomas and one transient hyperthyroidism), with no infections or nerve injury. Patient\u2010reported pain scores were 1 (IQR 1\u20102) and dropped by 43%. Overall satisfaction was 97% (66\/68). The improved sealed venous indwelling needle was significantly superior to the PTC needle in terms of procedural pain, comfort, complication rate, and overall patient experience (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05), whereas no statistically significant differences were observed in recovery speed, involution efficacy, operator skill, or communication clarity (\n                      <jats:italic>p<\/jats:italic>\n                      \u2265 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The improved sealed venous indwelling needle provides higher technical success, greater cyst volume reduction, fewer complications, and less pain than PTC needles, offering a safer and more effective alternative for ultrasound\u2010guided thyroid cyst sclerotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/rrp\/5868827","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T14:40:17Z","timestamp":1785508817000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Improved Sealed Venous Indwelling Needle in Ultrasound\u2010Guided Thyroid Cyst Puncture Sclerotherapy: Characteristics and Applications"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8940-4017","authenticated-orcid":false,"given":"Qing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7457-1153","authenticated-orcid":false,"given":"Guihua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3201-825X","authenticated-orcid":false,"given":"Guoyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"e_1_2_11_1_2","unstructured":"ChenY. ChenD. SongS.et al. HRDE: Retrieval-Augmented Large Language Models for Chinese Health Rumor Detection and Explainability 2024 https:\/\/doi.org\/10.48550\/ARXIV.2407.00668."},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/324581"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10023-1181"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1530\/ETJ-23-0085"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn115689-20220210-00547"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2015.16.6.1332"},{"key":"e_1_2_11_7_2","first-page":"1588","article-title":"Observation on Curative Effeot of Ultrasound-Guided Puncture and Sclerotheropy by Anhghrous Ethanol to the Elderly Benign Thyroid Cysts","volume":"27","author":"Feng L.","year":"2017","journal-title":"Yi Xue Ying Xiang Xue Za Zhi"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1674-9316.2016.10.120"},{"key":"e_1_2_11_9_2","first-page":"22","article-title":"Application Value of Intravenous Indwelling Needle in the Treatment of Thyroid Cystic Solid Nodular Sclerosis","volume":"12","author":"Dongmei S.","year":"2017","journal-title":"Zhongguo Shiyong Yiyao"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2013.0612"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14482"},{"key":"e_1_2_11_12_2","doi-asserted-by":"crossref","unstructured":"FeiD. LiY. andSuiG. Analysis on Effect and Relevant Factors of Ultrasound-Guided Lauromacrogol Sclerotherapy to Benign Thyroid Cyst Proceedings of the 2018 International Workshop on Bioinformatics Biochemistry Biomedical Sciences (BBBS 2018) 2018 Atlantis Press https:\/\/doi.org\/10.2991\/bbbs-18.2018.3.","DOI":"10.2991\/bbbs-18.2018.3"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2024.0082"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2024.104259"}],"container-title":["Radiology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/rrp\/5868827","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/rrp\/5868827","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/rrp\/5868827","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T14:40:20Z","timestamp":1785508820000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/rrp\/5868827"}},"subtitle":[],"editor":[{"given":"Satabdi","family":"Datta Choudhury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/rrp\/5868827"],"URL":"https:\/\/doi.org\/10.1155\/rrp\/5868827","archive":["Portico"],"relation":{},"ISSN":["2090-1941","2090-195X"],"issn-type":[{"value":"2090-1941","type":"print"},{"value":"2090-195X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5868827"}}