{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T22:32:50Z","timestamp":1782340370978,"version":"3.54.5"},"reference-count":0,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1826,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1826,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Secr\u00e9tariat d\u2019Etat \u00e0 la Recherche Scientifique et Technique, Tunisia"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mediators of Inflammation"],"published-print":{"date-parts":[[1995,1]]},"abstract":"<jats:p>The aim of this study was to evaluate circulating intercellular adhesion molecule\u20101 (cICAM\u20101) in serum and in bronchoalveolar lavage (BAL), as a marker for the inflammatory process in patients with active Beh\u00e7et\u2032s disease (BD). Circulating ICAM\u20101 was tested by an enzyme linked immuno\u2010sorbent assay in serum and in BAL of patients with BD. These values were compared to those of patients with tuberculosis and to healthy controls. Increased levels of circulating ICAM\u20101 were found in serum from patients with active BD compared to healthy controls (p &lt; 0.01). Similar levels of serum cICAM\u20101 were found in BD and tuberculosis. Additionally, both BD and tuberculosis patients exhibited high levels of cICAM\u20101 in BAL fluid, suggesting that this increase may be a result of the immune system activation in inflammatory sites. Circulating ICAM\u20101 seemed to have a good discriminative power in identifying active BD, being elevated in all active stages (p &lt; 0.01) compared to remission BD stage. No differences were found in active BD patients depending upon the clinical manifestations. These results suggest that cICAM\u20101 may be involved in leucocyte adhesion and migration into the vessel wall of the lung. Circulating forms are derived from molecules expressed on the surface of activated cells, as a result of an inflammatory process.<\/jats:p>","DOI":"10.1155\/s0962935195000573","type":"journal-article","created":{"date-parts":[[2007,3,14]],"date-time":"2007-03-14T11:15:28Z","timestamp":1173870928000},"page":"355-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Circulating intercellular adhesion molecules in blood and bronchoalveolar lavage in Beh\u00e7et\u2032s disease"],"prefix":"10.1155","volume":"4","author":[{"given":"A.","family":"Hamzaoui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Hamzaoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Chabbou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Ayed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1995,1]]},"container-title":["Mediators of Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/mi\/1995\/849798.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S0962935195000573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T04:29:30Z","timestamp":1723091370000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S0962935195000573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1995,1]]}},"alternative-id":["10.1155\/S0962935195000573"],"URL":"https:\/\/doi.org\/10.1155\/s0962935195000573","archive":["Portico"],"relation":{},"ISSN":["0962-9351","1466-1861"],"issn-type":[{"value":"0962-9351","type":"print"},{"value":"1466-1861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,1]]},"assertion":[{"value":"2000-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}