{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T19:10:08Z","timestamp":1790968208276,"version":"4.1.0"},"reference-count":0,"publisher":"Wiley","issue":"3-4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p><jats:italic>Objectives:<\/jats:italic> While early\u2010onset neonatal GBS sepsis is positively associated with premature birth and\nprolonged rupture of membranes, there is debate in the literature as to whether maternal GBS\ncolonization is a predictor of adverse obstetric outcome. This is a critical issue to resolve for\nappropriate management (expectant vs. interventional management) of the patient presenting with premature rupture of membranes, who has no overt signs of sepsis, but who is colonized with GBS.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> Since 1981 it has been hospital policy to screen all public patients antenatally for genital\ncarriage of GBS by collection of a low vaginal swab at 28\u201332 weeks. All patients colonized with GBS antenatally are given penicillin as intrapartum chemoprophylaxis. Review of all GBScolonized\nantenatal patients for a 12\u2010month period (580 of 4,495 patients) and a randomized (every fourth consecutive antenatal patient) number of noncolonized patients (958) was made. Lower vaginal GBS colonization and other risk factors for preterm delivery were assessed using univariate and multivariate generalized linear modeling.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> In the study group, the maternal GBS colonization rate was 12.9%. When cofounding\nvariables were controlled in a multivariate analysis, the association between antepartum GBS colonization and preterm labor and preterm rupture of membranes was not significant.<\/jats:p><jats:p><jats:italic>Conclusion:<\/jats:italic> Maternal antenatal carriage of GBS does not predict preterm labor. Therefore it is appropriate that expectant management occur for a GBS\u2010colonized woman who ruptures her membranes, is not in labor, and has no evidence of sepsis. Infect. Dis. Obstet. Gynecol. 8:138\u2013142, 2000.<\/jats:p>","DOI":"10.1155\/s106474490000017x","type":"journal-article","created":{"date-parts":[[2007,3,7]],"date-time":"2007-03-07T13:06:12Z","timestamp":1173272772000},"page":"138-142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Is Antenatal Group B Streptococcal Carriage aPredictor of Adverse Obstetric Outcome?"],"prefix":"10.1155","volume":"8","author":[{"given":"Suzanne M.","family":"Garland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antony M.","family":"Ugoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2000,3,20]]},"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2000\/486279.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2000\/486279.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S106474490000017X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T19:53:49Z","timestamp":1723060429000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S106474490000017X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":0,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1155\/S106474490000017X"],"URL":"https:\/\/doi.org\/10.1155\/s106474490000017x","archive":["Portico"],"relation":{},"ISSN":["1064-7449"],"issn-type":[{"value":"1064-7449","type":"print"}],"subject":[],"published":{"date-parts":[[2000,1]]},"assertion":[{"value":"1999-05-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2000-03-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2000-03-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}