{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:33:04Z","timestamp":1779931984221,"version":"3.53.1"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":2191,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":2191,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[1994,1]]},"abstract":"<jats:p><jats:italic>Objective:<\/jats:italic> This retrospective investigation describes the infectious morbidity of patients following\nradical vulvectomy with or without inguinal lymph node dissection.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> The charts of patients undergoing radical vulvectomy between January 1, 1986, and\nSeptember 1, 1989, were reviewed for age, weight, cancer type, tumor stage, operative procedure(s), prophylactic \nantibiotic and its length of use, febrile morbidity, infection site, culture results, significant medical history, and length\nof use and number of drains or catheters used.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> The study group was composed of 61 patients, 14 of whom underwent a radical vulvectomy\nand 47 who also had inguinal lymph node dissection performed. Twenty\u2010nine patients (48%) had at least 1 \npostoperative infection. Five patients (8%) had 2 or more postoperative infections. The site and incidence of the\ninfections were as follows: urinary tract 23%, wound 23%, lymphocyst 3%, lymphatics (lymphangitis)\n5%, and bowel (pseudomembranous colitis) 3%. The most common pathogens isolated from both urine and\nwound sites were <jats:italic>Pseudomonas aeruginosa<\/jats:italic>, enterococcus, and <jats:italic>Escherichia coli.<\/jats:italic> A significant decrease in wound \ninfection was demonstrated when separate incisions were made for inguinal lymph node dissection (<jats:italic>P<\/jats:italic> &lt;0.05). \nThe mean number of days to onset of postoperative infection for wound, urine, lymphatics, lymphocyst, and bowel were\n11, 8, 57, 48, and 5, respectively.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> We conclude that the clinical appearance of post\u2010radical vulvectomy infections is\ndelayed when compared with other post\u2010surgical wound infections. Second, utilizing separate inguinal surgical\nincisions may reduce infectious morbidity. Finally, tumor stage and type do not necessarily increase the infectious\nmorbidity of radical vulvar surgery.<\/jats:p>","DOI":"10.1155\/s1064744994000529","type":"journal-article","created":{"date-parts":[[2007,3,7]],"date-time":"2007-03-07T13:01:22Z","timestamp":1173272482000},"page":"130-135","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Infectious Morbidity After Radical Vulvectomy"],"prefix":"10.1155","volume":"2","author":[{"given":"Steven A.","family":"Elg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda F.","family":"Carson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris C.","family":"Brooker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan R.","family":"Carter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo B.","family":"Twiggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1994,5,18]]},"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/1994\/590760.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/1994\/590760.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S1064744994000529","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T19:57:47Z","timestamp":1723060667000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S1064744994000529"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1994,1]]}},"alternative-id":["10.1155\/S1064744994000529"],"URL":"https:\/\/doi.org\/10.1155\/s1064744994000529","archive":["Portico"],"relation":{},"ISSN":["1064-7449"],"issn-type":[{"value":"1064-7449","type":"print"}],"subject":[],"published":{"date-parts":[[1994,1]]},"assertion":[{"value":"1994-01-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1994-05-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2000-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}