{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:10:03Z","timestamp":1723065003464},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1826,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1826,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[1995,1]]},"abstract":"<jats:p><jats:italic>Objective:<\/jats:italic> This study was to determine the significance of meconium in the amniotic fluid of pregnancies complicated by preterm premature rupture of membranes (PPROM) without labor.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> A case\u2010control study of 31 pregnancies complicated by PPROM at 27\u201336 weeks gestation with meconium present (study group) and 93 pregnancies complicated by PPROM but without meconium was performed. The patients were matched for year of delivery, gestational age, race, and parity. Pregnancy and neonatal outcome variables of the 2 groups were compared.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> The incidence of early onset neonatal sepsis was significantly increased in the study group (16.1% vs. 1.1%; <jats:italic>P<\/jats:italic> &lt; 0.001). Similarly, chorioamnionitis (48.3% vs. 22.5%; <jats:italic>P<\/jats:italic> &lt; 0.01), cesarean delivery for a nonreassuring fetal heart rate pattern (19.4% vs. 3.2%; <jats:italic>P<\/jats:italic> &lt; 0.01), a 5\u2010min Apgar score &lt; 7 (22.5% vs. 8.6%; <jats:italic>P<\/jats:italic> &lt; 0.05), and fetal growth retardation (FGR) (12.9% vs. 2.2%; <jats:italic>P<\/jats:italic> &lt; 0.05) were also more common in pregnancies complicated by PPROM with meconium. The mean umbilical cord arterial pH was significantly lower in these pregnancies (7.18 \u00b1 0.07 vs. 7.28 \u00b1 0.08;\n<jats:italic>P<\/jats:italic> &lt; 0.001). After controlling for confounding variables with multiple logistic regression analysis, we found that meconium in the amniotic fluid remained associated with early onset neonatal sepsis.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> The presence of meconium in the amniotic fluid of pregnancies complicated by\nPPROM is associated with an increased incidence of early onset neonatal group B \u03b2\u2010hemolytic streptococcus (GBBS) sepsis.<\/jats:p>","DOI":"10.1155\/s1064744995000251","type":"journal-article","created":{"date-parts":[[2007,3,7]],"date-time":"2007-03-07T13:31:25Z","timestamp":1173274285000},"page":"22-27","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Meconium in the Amniotic Fluid of Pregnancies Complicated by Preterm Premature Ruptureof Membranes Is Associated With Early Onset Neonatal Sepsis"],"prefix":"10.1155","volume":"3","author":[{"given":"Michael J.","family":"Kupferminc","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Wickstrom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nam H.","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia M.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1995,3,7]]},"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/1995\/232639.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/1995\/232639.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S1064744995000251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T20:43:05Z","timestamp":1723063385000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S1064744995000251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1995,1]]}},"alternative-id":["10.1155\/S1064744995000251"],"URL":"https:\/\/doi.org\/10.1155\/s1064744995000251","archive":["Portico"],"relation":{},"ISSN":["1064-7449"],"issn-type":[{"type":"print","value":"1064-7449"}],"subject":[],"published":{"date-parts":[[1995,1]]},"assertion":[{"value":"1994-06-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1995-03-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2000-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}