{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:10:04Z","timestamp":1723065004942},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p><jats:italic>Objective:<\/jats:italic> The impact of anaerobic growth conditions on the <jats:italic>Staphylococcus aureus<\/jats:italic> toxic shock syndrome\ntoxin\u20101 (TSST\u20101) production was studied.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> Ten strains of <jats:italic>S. aureus<\/jats:italic> derived from patients with toxic shock syndrome (TSS), 10\nisolates of <jats:italic>S. aureus<\/jats:italic>, and documented TSST\u20101\u2010producing strains recovered from patients with either\nstaphylococcal septicemia or staphylococcal nongenital abscesses were grown under aerobic and\nanaerobic conditions. The bacterial growth was measured using optical density (OD) determinations\nat 520 nm. The toxin production was assayed using the TS\u2010RPLA latex agglutination test.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> Both TSS and non\u2010TSS strains of <jats:italic>S. aureus<\/jats:italic> grown under aerobic and anaerobic conditions\nexhibited comparable OD patterns of growth, and the levels of toxin production remained constant\nduring the logarithmic phase. Toxin titers developed during the logarithmic growth phase and\npeaked after 24 h of incubation. When stationary\u2010phase isolates grown initially under aerobic\nconditions were subjected to strict anaerobic conditions, subsequent toxin titers, compared with\nisolates grown in the continued presence of oxygen, were depressed 2\u2010fold, peaking at a later time.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> TSST\u20101 production is diminished under continued anaerobic conditions.<\/jats:p>","DOI":"10.1155\/s1064744996000440","type":"journal-article","created":{"date-parts":[[2007,3,7]],"date-time":"2007-03-07T13:01:43Z","timestamp":1173272503000},"page":"232-238","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Anaerobic Growth Conditions on Toxic Shock Syndrome Toxin\u2010I Production by <i>Staphylococcus aureus<\/i>"],"prefix":"10.1155","volume":"4","author":[{"given":"Max","family":"Lungren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pongsakdi","family":"Chaisilwattana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floyd C.","family":"Knoop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles R. G.","family":"Monif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1996,7,17]]},"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/1996\/250651.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/1996\/250651.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S1064744996000440","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T20:45:46Z","timestamp":1723063546000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S1064744996000440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1155\/S1064744996000440"],"URL":"https:\/\/doi.org\/10.1155\/s1064744996000440","archive":["Portico"],"relation":{},"ISSN":["1064-7449"],"issn-type":[{"type":"print","value":"1064-7449"}],"subject":[],"published":{"date-parts":[[1996,1]]},"assertion":[{"value":"1996-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-07-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-07-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}