{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:23:09Z","timestamp":1789474989986,"version":"build-2803163510"},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Analytical Methods in Chemistry"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:p>The lack of standardization of methods to measure cardiac markers for coronaria ischaemia, particularly troponin, led us to perform an analytical evaluation of two new immunoassays to quantify CK\u2010MB mass and troponin I using the Dimension R\u00d7L automatic analyser. The reliability and analytical intervals of the methods were studied as well as reference values (0.010\u2014 0.228 \u03bcg l<jats:sup>-1<\/jats:sup> for troponin I, 0.20\u20143.90 mg \u03bcg l<jats:sup>-1<\/jats:sup> for CK\u2010MB mass) and cuto\u00a1 values (0.77 \u03bcg l<jats:sup>-1<\/jats:sup> for troponin I, 5 \u03bcg l<jats:sup>-1<\/jats:sup> for CK\u2010MB mass) established. The cutoff values were established from 37 patients with acute myocardial infarction and from 20 with unstable angina. The absence of method cross\u2010reactivity was corroborated using myocardial, brain and skeletal muscle tissue. Both methods were highly specific and showed good reliability and practicability in the diagnosis of coronaria ischaemia after 6 h of precordial pain.<\/jats:p>","DOI":"10.1155\/s146392460200010x","type":"journal-article","created":{"date-parts":[[2007,3,8]],"date-time":"2007-03-08T08:53:36Z","timestamp":1173344016000},"page":"51-57","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analytical evaluation of two automatic methods to measure blood CK\u2010MB mass and troponin I"],"prefix":"10.1155","volume":"24","author":[{"given":"Amparo","family":"Gal\u00e1n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Curos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Duran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto","family":"Corominas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Valle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,1]]},"container-title":["Journal of Analytical Methods in Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jamc\/2002\/874508.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S146392460200010X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:12:57Z","timestamp":1723075977000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S146392460200010X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1155\/S146392460200010X"],"URL":"https:\/\/doi.org\/10.1155\/s146392460200010x","archive":["Portico"],"relation":{},"ISSN":["2090-8865","2090-8873"],"issn-type":[{"value":"2090-8865","type":"print"},{"value":"2090-8873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,1]]},"assertion":[{"value":"2002-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}