{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:54:17Z","timestamp":1760853257029},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1826,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1826,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Japan Health Science Foundation"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Analytical Methods in Chemistry"],"published-print":{"date-parts":[[1995,1]]},"abstract":"<jats:p>A fully automated apparatus for the synthesis and formulation of short\u2010lived <jats:sup>11<\/jats:sup>C (t<jats:sub>1\/2<\/jats:sub> = 20 min)\u2010labeled carboxylic acids for\npositron emission tomograpy (PET) has been developed. Injectable solutions of [1\u2010<jats:sup>11<\/jats:sup>C]acetic acid, [1\u2010<jats:sup>11<\/jats:sup>C]octanoic acid and [1\u2010<jats:sup>11<\/jats:sup>C]palmitic acid wilh radioactivities of 6.36\u20108.29 GBq, 0.070\u20101.43 GBq and 0.42\u20100.89 GBq were obtained. The preparation time was under 40 min after the end of bombardment.\nAn automatic washing function means that labeled compound of the same or different kinds can be produced several times a day without any maintenance of the system. The control system is sited away from the \u2018hot laboratory\u2019, so operator exposure to radiation is minimized.<\/jats:p>","DOI":"10.1155\/s1463924695000198","type":"journal-article","created":{"date-parts":[[2007,3,8]],"date-time":"2007-03-08T08:53:36Z","timestamp":1173344016000},"page":"109-114","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Automated synthesis of radiopharmaceuticals for positron emissiontomography: an apparatus for [1\u2010<sup>11<\/sup>C] labeled carboxylic acid"],"prefix":"10.1155","volume":"17","author":[{"given":"Kazuyoshi","family":"Yajima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyoshi","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidefumi","family":"Kawashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sento","family":"Ino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyoshi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1995,1]]},"container-title":["Journal of Analytical Methods in Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jamc\/1995\/796589.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S1463924695000198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T20:15:01Z","timestamp":1723061701000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S1463924695000198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,1]]}},"alternative-id":["10.1155\/S1463924695000198"],"URL":"https:\/\/doi.org\/10.1155\/s1463924695000198","archive":["Portico"],"relation":{},"ISSN":["2090-8865","2090-8873"],"issn-type":[{"type":"print","value":"2090-8865"},{"type":"electronic","value":"2090-8873"}],"subject":[],"published":{"date-parts":[[1995,1]]},"assertion":[{"value":"2000-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}