{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:03:25Z","timestamp":1789538605785,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":257,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Stroke Research and Treatment"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Stroke among young adults is a growing public health problem in sub\u2010Saharan Africa, where hypertension is the leading modifiable risk factor for cerebrovascular injury (CVI). We aimed to describe hypertension patterns and associated CVI among young adults with stroke in Senegal. We conducted a cross\u2010sectional study among adults aged \u2264\u200950 years with neuroimaging\u2010confirmed stroke in Senegal. We collected demographic characteristics, vascular risk factors, blood pressure parameters, MRI findings, and clinical outcomes. Hypertension was categorized as previously diagnosed, newly diagnosed, treated, or untreated. We performed multivariable analyses to identify predictors of stroke severity, CVI, and outcomes. A total of 94 patients were included, with a mean age of 45.0 \u00b1 4.3 years; 55.3% were female. Mean admission systolic and diastolic blood pressures were 150.31 \u00b1 31.8\u2009mmHg and 90.83 \u00b1 22.03\u2009mmHg, respectively, and  42.5% presented with severe hypertension. Primary hypertension accounted for 97.9% of hypertension cases. White matter hyperintensities were the most frequent marker of CVI and were significantly associated with stroke severity (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.016) and poorer functional outcomes at discharge (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.035). In multivariable regression, CVI remained significantly associated with stroke severity (\n                    <jats:italic>B<\/jats:italic>\n                    = 3.35, 95% CI 0.18\u20136.49,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.032). Hemorrhagic stroke was associated with higher admission systolic and diastolic blood pressure (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.001 for both). Young adults in this cohort demonstrated a high burden of hypertension\u2010related CVI.\n                  <\/jats:p>","DOI":"10.1155\/srat\/4927580","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:18:01Z","timestamp":1789535881000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypertension Characteristics and Neuroimaging Markers of Cerebrovascular Injury in Young Hypertensive Adults With Acute Cerebrovascular Events"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2168-8516","authenticated-orcid":false,"given":"Mundih Noelar","family":"Njohjam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1678-1460","authenticated-orcid":false,"given":"Tiffany Falonne","family":"Niakam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1761-628X","authenticated-orcid":false,"given":"Mark Olivier","family":"Ngoule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"e_1_2_12_1_2","volume-title":"Global Report on Hypertension 2025","author":"World Health Organization","year":"2025"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.124.323889"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26010123"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/10641963.2026.2631606"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx330"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.2174\/1570161115666171116151051"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11831-x"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics15202585"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.04394"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.14.04136"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-024-00913-6"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-024-00957-8"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-023-00873-3"},{"key":"e_1_2_12_14_2","volume-title":"Stroke Care Quality Registry","author":"RES-Q","year":"2026"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0301547"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-022-13877-4"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)02208-1"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0219623"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.124.23508"},{"key":"e_1_2_12_20_2","doi-asserted-by":"publisher","DOI":"10.13140\/RG.2.2.20765.63205"},{"key":"e_1_2_12_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5813-z"},{"key":"e_1_2_12_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2024.107952"},{"key":"e_1_2_12_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.11.062"},{"key":"e_1_2_12_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.540112"},{"key":"e_1_2_12_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2018.3122"},{"key":"e_1_2_12_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2005.11.001"},{"key":"e_1_2_12_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30079-1"},{"key":"e_1_2_12_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-024-01797-2"},{"key":"e_1_2_12_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2018.05.018"},{"key":"e_1_2_12_30_2","doi-asserted-by":"publisher","DOI":"10.1159\/000450962"},{"key":"e_1_2_12_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2024.123071"},{"key":"e_1_2_12_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-020-00797-x"}],"container-title":["Stroke Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/srat\/4927580","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/srat\/4927580","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/srat\/4927580","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:18:03Z","timestamp":1789535883000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/srat\/4927580"}},"subtitle":[],"editor":[{"given":"Domenico Maria","family":"Mezzapesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1155\/srat\/4927580"],"URL":"https:\/\/doi.org\/10.1155\/srat\/4927580","archive":["Portico"],"relation":{},"ISSN":["2090-8105","2042-0056"],"issn-type":[{"value":"2090-8105","type":"print"},{"value":"2042-0056","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-06-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4927580"}}