{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:59:38Z","timestamp":1792717178719,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,13]],"date-time":"2006-07-13T00:00:00Z","timestamp":1152748800000},"content-version":"vor","delay-in-days":193,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Genetronics Inc, San Diego"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Sarcoma"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. Examination of the potential of electroporation therapy (EPT) in a patient with metastatic soft tissue sarcoma. <jats:italic>Patient<\/jats:italic>. A 24\u2010year\u2010old male who underwent extensive resection and postoperative radiotherapy for a malignant peripheral nerve sheath tumor in the right infratemporal fossa with intracranial extension and invasion of the maxillary sinus and mandible had a recurrence in the scar of his craniotomy for which he was initially treated with doxorubicin. After discontinuation of doxorubicin he developed a metastatic mass at the same site for which he was treated with electroporation therapy. <jats:italic>Method<\/jats:italic>. The subcutaneous metastasis was infiltrated with bleomycin and electroporated. <jats:italic>Results<\/jats:italic>. Gradually the tumor became increasingly necrotic and demarcated from surrounding tissue. After 10 weeks no tumor was seen anymore. The wound healed secondarily. <jats:italic>Discussion<\/jats:italic>. Intralesional bleomycin followed by EPT is potentially effective, well tolerated, and easy to perform in well accessible soft tissue sarcoma sites.<\/jats:p>","DOI":"10.1155\/srcm\/2006\/85234","type":"journal-article","created":{"date-parts":[[2006,8,2]],"date-time":"2006-08-02T19:14:38Z","timestamp":1154546078000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Electroporation Therapy in Soft Tissue Sarcoma: A Potentially Effective Novel Treatment"],"prefix":"10.1155","volume":"2006","author":[{"given":"Remco","family":"de Bree","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard M.","family":"Tijink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cees J.","family":"van Groeningen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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