{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T09:27:46Z","timestamp":1786440466023,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":222,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transboundary and Emerging Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:italic>Scutavirus testudinidalpha3<\/jats:italic>\n                    , formerly\n                    <jats:italic>Testudinid alphaherpesvirus<\/jats:italic>\n                    3 or testudinid herpesvirus (TeHV)\u20103, is a highly contagious herpesvirus that has been reported in multiple testudinid species, causing acute stomatitis\u2013rhinitis complex in affected animals or establishing latent infections in surviving individuals. This study investigated an outbreak of\n                    <jats:italic>S. testudinidalpha3<\/jats:italic>\n                    infection in 17 elongated tortoises (\n                    <jats:italic>Indotestudo elongata<\/jats:italic>\n                    ) housed exclusively in an outdoor zoo enclosure in Taiwan in March, 2022. The affected tortoises exhibited nasal and ocular discharge and diphtheroid plaques on the oral mucosa. Despite prompt isolation and supportive treatment, 14 individuals succumbed. Necropsy and histopathologic examination revealed severe necrosis with inflammation, characterized by eosinophilic intranuclear inclusion bodies and occasional syncytial cells in multiple organs. Conventional polymerase chain reaction (PCR) and in situ hybridization (ISH) confirmed\n                    <jats:italic>S. testudinidalpha3<\/jats:italic>\n                    infection. DNA polymerase (DNApol) gene sequences were identical among all individuals and shared 97.86% nucleotide similarity with the German 4295\/7R strain. Furthermore, the full\u2010length sequence of glycoprotein B (gB), a potential virulence factor in herpesviruses, showed 99.9% identity with the Switzerland CH6883\/03 strain, classifying this isolate as belonging to the genogroup B, known for its high pathogenicity. This report documents the first confirmed case of\n                    <jats:italic>S<\/jats:italic>\n                    .\n                    <jats:italic>testudinidalpha3<\/jats:italic>\n                    infection in elongated tortoises.\n                  <\/jats:p>","DOI":"10.1155\/tbed\/2984888","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T08:30:20Z","timestamp":1786437020000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Identification and Characterization of\n                    <i>Scutavirus testudinidalpha3<\/i>\n                    Infection in Captive Elongated Tortoises (\n                    <i>Indotestudo elongata<\/i>\n                    )"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3338-1018","authenticated-orcid":false,"given":"Han-Yang","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Hsuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0098-0278","authenticated-orcid":false,"given":"Wei-Hsiang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8877-1886","authenticated-orcid":false,"given":"Hui-Wen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3941-6276","authenticated-orcid":false,"given":"Chain-Ren","family":"Jeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiu-Hung","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pao-Jung","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4971-4237","authenticated-orcid":false,"given":"Yen-Chen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.5818\/1529-9651-22.1-2.42"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/v3112087"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1638\/2009-0214R.1"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01794-15"},{"key":"e_1_2_11_5_2","first-page":"5","article-title":"Herpesviridae Causing Glossitis and Meningoencephalitis in Land Tortoises (Testudo hermanni)","volume":"1","author":"Heldstab A.","year":"1989","journal-title":"Herpetopathologia"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197169"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1638\/2008-0045.1"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.41-1-50"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.5818\/1529-9651-20.2.61"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.62.905"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.36-6-624"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2005.09.008"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.15654\/TPK-150843"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.642894"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.12834\/VetIt.3533.26977.2"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2006.05.018"},{"key":"e_1_2_11_17_2","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2021.733299","article-title":"Herpesviruses in Captive Chelonians in Europe Between 2016 and 2020","volume":"8","author":"Leineweber C.","year":"2021","journal-title":"Frontiers in Veterinary Science"},{"key":"e_1_2_11_18_2","first-page":"5","article-title":"Observations on the Feeding Ecology of Indotestudo elongata (Blyth, 1853) in the Wild in Cambodia and Vietnam","volume":"5","author":"Ihlow F.","year":"2012","journal-title":"Herpetol Notes"},{"key":"e_1_2_11_19_2","first-page":"212","article-title":"The Distribution of the Elongated Tortoise (Indotestudo elongata) on the Indian Subcontinent: Implications for Conservation and Management","volume":"15","author":"Khan S.","year":"2020","journal-title":"Herpetological Conservation and Biology"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.58837\/tnh.13.1.103039"},{"key":"e_1_2_11_21_2","unstructured":"RahmanS. 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