{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T07:57:43Z","timestamp":1780905463233,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"vor","delay-in-days":157,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFD1801005"],"award-info":[{"award-number":["2023YFD1801005"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQN25C180004"],"award-info":[{"award-number":["LQN25C180004"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transboundary and Emerging Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Colistin resistance genes have attracted increasing global attention due to their plasmid\u2010mediated transmissibility. To clarify the transmission dynamics of colistin resistance genes in the endangered crested ibis (\n                    <jats:italic>Nipponia nippon<\/jats:italic>\n                    ) and its environment, surveillance for\n                    <jats:italic>mcr-1<\/jats:italic>\n                    was conducted at a captive breeding center in Deqing, Zhejiang, China, from 2017 to 2024. Genomic sequencing was used to analyze the phylogenetic relationships among the Enterobacteriaceae isolates harboring these resistance genes. A total of 2660 fecal samples of crested ibises were collected seasonally. There was only one episode of\n                    <jats:italic>mcr-1<\/jats:italic>\n                    occurrence with a total of 144\n                    <jats:italic>mcr-1<\/jats:italic>\n                    \u2010positive strains in crested ibises. The prevalence was first detected at 8% in April 2021, surged to 25% in July, and then declined to 10.6% in October. Additionally,\n                    <jats:italic>mcr-1<\/jats:italic>\n                    \u2010harboring\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    isolates were also found in feces from wild egrets (33%), the staff member\u2019s dog (8.3%), and effluent sewage, but not in the staff member, loach samples, or water sources. Phylogenetic analysis showed that the egret\u2010derived isolate BLM86 and the crested ibis\u2010derived isolate ZHM12 belonged to the same ST58\u2010cgST28300 type; no core\u2010genome SNP differences were detected. All 36\u2010deeper analyzed\n                    <jats:italic>mcr-1<\/jats:italic>\n                    \u2010positive isolates displayed multidrug resistance, with four distinct\n                    <jats:italic>mcr-1<\/jats:italic>\n                    \u2010containing plasmid types identified: IncI2 (20\/36, 55.6%), IncX4 (19.4%), IncP1 (11.1%), and IncHI2 (13.9%). Phylogenetic analysis indicated that several of these crested ibis\u2010derived isolates were closely related to those from egrets, implying potential environmental transmission routes to both the crested ibis and egrets.\n                    <jats:italic>Mcr-1<\/jats:italic>\n                    was no longer detected in the crested ibis population after implementation of biosecurity interventions. Our findings demonstrate that wild egrets could act as potential vectors for the environmental transmission of\n                    <jats:italic>mcr-1<\/jats:italic>\n                    to captive crested ibises, highlighting the importance of interspecies barriers in antimicrobial resistance (AMR) containment.\n                  <\/jats:p>","DOI":"10.1155\/tbed\/4384955","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T06:59:02Z","timestamp":1780901942000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Egrets Promote the Transmission and Spread of Plasmid\u2010Mediated Colistin Resistance Gene\n                    <i>mcr-1<\/i>\n                    \u2010Bearing\n                    <i>Escherichia coli<\/i>\n                    Strains in Crested Ibis"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3223-4605","authenticated-orcid":false,"given":"Keyuan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wulin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqiang","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6795-9978","authenticated-orcid":false,"given":"Yadong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2460-0743","authenticated-orcid":false,"given":"Weihuan","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6530-5794","authenticated-orcid":false,"given":"Houhui","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2582-0311","authenticated-orcid":false,"given":"Yongchun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,7]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-017-0561-1"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03205-z"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2019.03.056"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005958"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00424-7"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)00061-X"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-15539-7"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2018.06.007"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2019.07.078"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2022.03.016"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.115200"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.164102"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw262"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw245"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01346-22"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2021.09.009"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/cmb.2012.0021"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000192"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.06094-11"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkaa345"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab1107"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-9877-7"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0524-x"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst028"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.12688\/wellcomeopenres.14694.1"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab301"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(20)30005-7"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c01633"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.26486-0"},{"key":"e_1_2_11_30_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2020.0242"},{"key":"e_1_2_11_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01204-16"},{"key":"e_1_2_11_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.118136"},{"key":"e_1_2_11_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2019.10.001"},{"key":"e_1_2_11_34_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00745"},{"key":"e_1_2_11_35_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-017-0288-0"},{"key":"e_1_2_11_36_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1717380"},{"key":"e_1_2_11_37_2","doi-asserted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